Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXE34_RS07620 Genome accession   NZ_CP035865
Coordinates   1605576..1606232 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E275 a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1600576..1611232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXE34_RS07590 dcyD 1601455..1602441 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  EXE34_RS07595 tcyL 1602456..1603124 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXE34_RS07600 tcyN 1603121..1603873 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXE34_RS07605 sdiA 1604103..1604825 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  EXE34_RS07610 yecF 1604893..1605117 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXE34_RS07615 yecU 1605104..1605280 (-) 177 WP_000590344.1 protein YecU -
  EXE34_RS27015 - 1605318..1605434 (-) 117 WP_001302039.1 hypothetical protein -
  EXE34_RS07620 letA 1605576..1606232 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXE34_RS07625 uvrC 1606229..1608061 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  EXE34_RS07630 pgsA 1608118..1608666 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXE34_RS07650 yecA 1609315..1609980 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=306043 EXE34_RS07620 WP_000611328.1 1605576..1606232(+) (letA) [Escherichia coli strain E275 a]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=306043 EXE34_RS07620 WP_000611328.1 1605576..1606232(+) (letA) [Escherichia coli strain E275 a]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482