Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA00_RS09355 Genome accession   NZ_CP035860
Coordinates   1954220..1954876 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TD225-C4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949220..1959876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA00_RS09325 dcyD 1950099..1951085 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  EXA00_RS09330 tcyL 1951100..1951768 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA00_RS09335 tcyN 1951765..1952517 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA00_RS09340 sdiA 1952747..1953469 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  EXA00_RS09345 yecF 1953537..1953761 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA00_RS09350 yecU 1953748..1953924 (-) 177 WP_000590347.1 protein YecU -
  EXA00_RS26600 - 1954007..1954078 (-) 72 Protein_1830 transcriptional regulator -
  EXA00_RS09355 letA 1954220..1954876 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA00_RS09360 uvrC 1954873..1956705 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA00_RS09365 pgsA 1956762..1957310 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA00_RS09385 yecA 1957960..1958625 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305980 EXA00_RS09355 WP_000611335.1 1954220..1954876(+) (letA) [Escherichia coli strain TD225-C4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305980 EXA00_RS09355 WP_000611335.1 1954220..1954876(+) (letA) [Escherichia coli strain TD225-C4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment