Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV143_RS13725 Genome accession   NZ_CP031333
Coordinates   1435187..1435651 (-) Length   154 a.a.
NCBI ID   WP_162467419.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18727     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1422657..1441823 1435187..1435651 within 0


Gene organization within MGE regions


Location: 1422657..1441823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS08425 neuA 1422657..1423343 (+) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -
  DV143_RS08430 siaC 1423344..1424393 (+) 1050 WP_002215299.1 polysialic acid capsule biosynthesis protein SiaC -
  DV143_RS08435 - 1424477..1425964 (+) 1488 WP_002215303.1 alpha-2,8-polysialyltransferase family protein -
  DV143_RS08445 - 1426460..1427413 (-) 954 WP_002215304.1 DUF6716 putative glycosyltransferase -
  DV143_RS08450 galE 1427796..1428815 (+) 1020 WP_115435274.1 UDP-glucose 4-epimerase GalE -
  DV143_RS08455 rfbB 1428931..1429956 (+) 1026 WP_002236574.1 dTDP-glucose 4,6-dehydratase -
  DV143_RS08460 rfbA 1430062..1430928 (+) 867 WP_061732524.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DV143_RS08465 rfbC 1430982..1431539 (+) 558 WP_002220108.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  DV143_RS08470 - 1431583..1433601 (-) 2019 WP_002220107.1 oligopeptide transporter, OPT family -
  DV143_RS08475 dnaJ 1433797..1434918 (-) 1122 WP_002220105.1 molecular chaperone DnaJ -
  DV143_RS14095 - 1435000..1435158 (-) 159 WP_002215272.1 hypothetical protein -
  DV143_RS13725 comE 1435187..1435651 (-) 465 WP_162467419.1 ComEA family DNA-binding protein Machinery gene
  DV143_RS08520 dksA 1441407..1441823 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16573.86 Da        Isoelectric Point: 10.8645

>NTDB_id=305954 DV143_RS13725 WP_162467419.1 1435187..1435651(-) (comE) [Neisseria meningitidis strain M18727]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=305954 DV143_RS13725 WP_162467419.1 1435187..1435651(-) (comE) [Neisseria meningitidis strain M18727]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGACCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCGGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment