Detailed information    

insolico Bioinformatically predicted

Overview

Name   comL   Type   Machinery gene
Locus tag   DV143_RS12965 Genome accession   NZ_CP031333
Coordinates   2197486..2198289 (-) Length   267 a.a.
NCBI ID   WP_002227520.1    Uniprot ID   A0A112L5W0
Organism   Neisseria meningitidis strain M18727     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 2192486..2203289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS12960 comA 2195209..2197428 (+) 2220 WP_153063236.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DV143_RS12965 comL 2197486..2198289 (-) 804 WP_002227520.1 outer membrane protein assembly factor BamD Machinery gene
  DV143_RS12970 rluD 2198288..2199412 (+) 1125 WP_014581515.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  DV143_RS12975 - 2199564..2200511 (-) 948 WP_002219577.1 bile acid:sodium symporter family protein -
  DV143_RS12985 pgeF 2201117..2201896 (+) 780 WP_002221253.1 peptidoglycan editing factor PgeF -
  DV143_RS12990 lptE 2201948..2202427 (+) 480 WP_002214127.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30790.84 Da        Isoelectric Point: 9.1698

>NTDB_id=305948 DV143_RS12965 WP_002227520.1 2197486..2198289(-) (comL) [Neisseria meningitidis strain M18727]
MKKILLTVSLGLALSACATKGTVDKDAQITQDWSVEKLYAEAQDELNSSNYTRAVKLYEILESRFPTSRHARQSQLDTAY
AYYKDDEKDKALAAIERFRRLHPQHPNMDYALYLRGLVLFNEDQSFLNKLASQDWSDRDPKANREAYQAFAELVQRFPNS
KYAADATARMVKLVDALGGNEISVARYYMKRGAYIAAANRAQKIIGSYQNTRYVEESLAILELAYQKLGKPQLAADTRRV
LETNFPKSPFLTHAWQPDDMPWWRYWH

Nucleotide


Download         Length: 804 bp        

>NTDB_id=305948 DV143_RS12965 WP_002227520.1 2197486..2198289(-) (comL) [Neisseria meningitidis strain M18727]
ATGAAAAAAATTCTTTTAACGGTTTCATTAGGTTTGGCACTGAGTGCCTGTGCCACCAAAGGTACGGTAGATAAAGATGC
CCAAATTACCCAAGACTGGAGTGTGGAAAAACTCTATGCCGAAGCCCAGGACGAATTGAACAGCAGCAATTATACGCGGG
CTGTCAAGTTATACGAAATCTTGGAATCGCGCTTCCCCACCAGCCGCCATGCCCGGCAGTCGCAACTGGATACCGCATAC
GCCTATTATAAAGACGATGAAAAAGACAAAGCTCTGGCGGCAATCGAACGCTTCCGCCGCCTTCACCCGCAACACCCGAA
TATGGATTACGCGCTGTATCTGCGCGGCTTGGTGCTGTTCAACGAAGACCAGTCCTTCTTGAACAAACTGGCCTCGCAAG
ACTGGTCCGACCGCGACCCGAAAGCCAACCGCGAAGCGTACCAGGCGTTTGCGGAACTCGTCCAACGCTTCCCGAACAGC
AAATACGCCGCCGATGCAACCGCACGCATGGTCAAACTGGTCGATGCACTGGGCGGCAATGAAATATCGGTGGCGCGCTA
CTACATGAAACGCGGTGCATACATCGCCGCCGCCAACCGCGCCCAAAAAATCATCGGCAGCTACCAGAATACGCGTTATG
TCGAAGAATCGCTCGCCATATTGGAACTTGCCTACCAAAAACTCGGCAAACCACAGCTTGCCGCCGATACGCGCCGCGTG
TTGGAAACCAACTTCCCGAAAAGCCCGTTTTTGACGCACGCTTGGCAGCCCGACGATATGCCCTGGTGGCGTTACTGGCA
TTAA

Domains

Predicted by InterproScan.

Outer membrane lipoprotein (YfiO)

(34-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A112L5W0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comL Neisseria gonorrhoeae MS11

97.753

100

0.978
  comL Neisseria meningitidis MC58

95.506

100

0.955

Multiple sequence alignment