Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   DV143_RS07235 Genome accession   NZ_CP031333
Coordinates   1220590..1221288 (-) Length   232 a.a.
NCBI ID   WP_014575140.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18727     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1215590..1226288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS07220 - 1215822..1216946 (-) 1125 WP_162819260.1 peptidylprolyl isomerase -
  DV143_RS07225 - 1217051..1219459 (-) 2409 WP_002254130.1 LPS-assembly protein LptD -
  DV143_RS07230 amgK 1219529..1220533 (+) 1005 WP_002239466.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  DV143_RS07235 dsbA1 1220590..1221288 (-) 699 WP_014575140.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  DV143_RS07240 - 1221315..1221506 (+) 192 WP_002260368.1 hypothetical protein -
  DV143_RS07245 murJ 1221506..1223044 (+) 1539 WP_014581316.1 murein biosynthesis integral membrane protein MurJ -
  DV143_RS14555 - 1223048..1223179 (+) 132 WP_255304562.1 hypothetical protein -
  DV143_RS07250 - 1223176..1224132 (+) 957 WP_014581315.1 alpha/beta fold hydrolase -
  DV143_RS07255 trpC 1224183..1224965 (+) 783 WP_014581314.1 indole-3-glycerol phosphate synthase TrpC -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25248.84 Da        Isoelectric Point: 5.9457

>NTDB_id=305930 DV143_RS07235 WP_014575140.1 1220590..1221288(-) (dsbA1) [Neisseria meningitidis strain M18727]
MKSRHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKNVANSHIFDAMVNQKIKLQNPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=305930 DV143_RS07235 WP_014575140.1 1220590..1221288(-) (dsbA1) [Neisseria meningitidis strain M18727]
ATGAAATCCAGACACCTCGCCCTCGGCGTTGCCGCCCTGTTCGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAAATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAAATCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCTTACGAATCTCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGCAAATATAAAGTCGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

99.569

100

0.996
  dsbA2 Neisseria meningitidis MC58

76.19

81.466

0.621

Multiple sequence alignment