Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV143_RS06885 Genome accession   NZ_CP031333
Coordinates   1161556..1162416 (+) Length   286 a.a.
NCBI ID   WP_002220276.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18727     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1156556..1167416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS06860 dapD 1157105..1157926 (-) 822 WP_002228980.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  DV143_RS06865 - 1157936..1158127 (-) 192 WP_072104424.1 hypothetical protein -
  DV143_RS06870 pgi 1158097..1159740 (-) 1644 WP_014581327.1 glucose-6-phosphate isomerase -
  DV143_RS06880 pilG 1160250..1161482 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  DV143_RS06885 pilD 1161556..1162416 (+) 861 WP_002220276.1 A24 family peptidase Machinery gene
  DV143_RS06890 coaE 1162418..1163050 (+) 633 WP_002216402.1 dephospho-CoA kinase -
  DV143_RS06895 - 1163043..1163252 (+) 210 WP_002216401.1 DNA gyrase inhibitor YacG -
  DV143_RS06900 pilF 1163337..1165013 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DV143_RS06920 - 1165505..1165951 (-) 447 WP_002220271.1 DUF441 domain-containing protein -
  DV143_RS06925 ispB 1165956..1166930 (-) 975 WP_002226981.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31359.40 Da        Isoelectric Point: 8.2213

>NTDB_id=305927 DV143_RS06885 WP_002220276.1 1161556..1162416(+) (pilD) [Neisseria meningitidis strain M18727]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=305927 DV143_RS06885 WP_002220276.1 1161556..1162416(+) (pilD) [Neisseria meningitidis strain M18727]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAGCGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

96.14

99.65

0.958
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment