Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV163_RS13480 Genome accession   NZ_CP031330
Coordinates   1663953..1664417 (+) Length   154 a.a.
NCBI ID   WP_162467384.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M21955     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1664118..1675005 1663953..1664417 flank -299


Gene organization within MGE regions


Location: 1663953..1675005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV163_RS13480 comE 1663953..1664417 (+) 465 WP_162467384.1 ComEA family DNA-binding protein Machinery gene
  DV163_RS09955 comP 1664505..1664954 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  DV163_RS14035 - 1665115..1665438 (-) 324 WP_202052896.1 5'-nucleotidase -
  DV163_RS13775 - 1665569..1665721 (-) 153 WP_002223150.1 hypothetical protein -
  DV163_RS09975 - 1666078..1666722 (+) 645 WP_002223148.1 hypothetical protein -
  DV163_RS09980 - 1666738..1667829 (+) 1092 WP_002225876.1 XRE family transcriptional regulator -
  DV163_RS09985 - 1667862..1670066 (-) 2205 WP_306769987.1 DUF3418 domain-containing protein -
  DV163_RS14275 - 1670067..1671245 (-) 1179 Protein_1634 DUF3418 domain-containing protein -
  DV163_RS09990 lpt3 1671347..1672924 (-) 1578 WP_002223145.1 lipooligosaccharide phosphoethanolamine transferase -
  DV163_RS09995 - 1673136..1673318 (-) 183 WP_002223144.1 hypothetical protein -
  DV163_RS10000 - 1673362..1675005 (-) 1644 WP_002223143.1 AAA family ATPase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 10.9585

>NTDB_id=305857 DV163_RS13480 WP_162467384.1 1663953..1664417(+) (comE) [Neisseria meningitidis strain M21955]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=305857 DV163_RS13480 WP_162467384.1 1663953..1664417(+) (comE) [Neisseria meningitidis strain M21955]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGACCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment