Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV167_RS12355 Genome accession   NZ_CP031329
Coordinates   2090064..2093147 (-) Length   1027 a.a.
NCBI ID   WP_115430511.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22425     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2085064..2098147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV167_RS12320 - 2085836..2086225 (-) 390 WP_115430510.1 endonuclease domain-containing protein -
  DV167_RS12330 - 2087000..2087389 (-) 390 WP_002219820.1 endonuclease domain-containing protein -
  DV167_RS12335 carA 2087843..2088976 (-) 1134 WP_002223013.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV167_RS12355 pilC 2090064..2093147 (-) 3084 WP_115430511.1 PilC family type IV pilus tip adhesin Machinery gene
  DV167_RS12360 apbC 2093634..2094713 (-) 1080 WP_002251532.1 iron-sulfur cluster carrier protein ApbC -
  DV167_RS12370 - 2095078..2095587 (+) 510 WP_002251531.1 protein disulfide oxidoreductase -
  DV167_RS12380 nadR 2095930..2096370 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DV167_RS12385 hpaC 2096485..2096985 (+) 501 WP_002226700.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV167_RS12390 murU 2097003..2097698 (+) 696 WP_002236138.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1027 a.a.        Molecular weight: 112143.80 Da        Isoelectric Point: 9.8856

>NTDB_id=305807 DV167_RS12355 WP_115430511.1 2090064..2093147(-) (pilC) [Neisseria meningitidis strain M22425]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNEGNQLEVKQNGQYSTIKDKDREREYHHQGKRGGGGSVS
FNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADGLQKRNNAVDWIRTTRPGLAGYAYTSVICRSNPGCPKLVYKTQFT
FGNSGLAKKANGGGLDIYVDKSRDNSPIYKLKDHPWLGVSFNLSAKGTANDGKTINKFDEKNSNNNLVYTTESHPISLGD
GQREHTAMAYYLNAKLHLLDKKGIKDITDKTVQLGVLKPSIDVRQRQGAGWLNFWAKWDIKDNGQIPVKLGLQQVKAGRC
ITTPNPNPKSKALSPALTAPALWFGPVQNGKAQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEIKSK
EPSFTGRQTVIRLDGGVRHIQLDRNNEATGFNGNDGKNDTFGIVKEYSVNPETNEWKKVLLPWTVRGFSNDNEFAKFNKK
SDKYSQRYRIRDNNGNRNLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIESKDSNLA
KELRTFAEKGYVGDRYGVDGGFVLRQVEWKGQNRVFMFGAMGFGGRGAYALDLTKADGSDPTAVSLFDVKHDNSGKNSNN
SNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKQIDSADNKTALYVYDLESSGNLIKKIEVPNGKGGLSSPTLVDKDL
DGTVDIAYAGDRGGSMYRFDLSGNDPTKWSARAIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDNNDMQSIYGI
FDNDTAAGNANANLSGLGGGLLEQKLTQEDRTLFLTDYKRSDGSGSKGWVVNLQPGQRVTVKPTVVLRTAFVTIRKYKDN
GCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKKENGKSIPIGCMWKNNETVCPNGYVYDKPVNVRYLDEK
KTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPMCGMKRISWREVFY

Nucleotide


Download         Length: 3084 bp        

>NTDB_id=305807 DV167_RS12355 WP_115430511.1 2090064..2093147(-) (pilC) [Neisseria meningitidis strain M22425]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGGGAAACCAGCTCGAGGTAAAGCAGAATGGGC
AATATTCAACAATAAAGGACAAAGACAGGGAGCGCGAATATCATCATCAGGGCAAAAGAGGAGGAGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCCCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGGGCTGCAAAAGCGCAACAATGCCGTCGATTGGATTCGTACCACCCGGCCCGGGC
TGGCAGGCTACGCCTACACCAGCGTCATATGCAGAAGCAACCCAGGCTGTCCCAAACTTGTCTATAAAACCCAATTTACC
TTCGGTAATTCCGGTTTGGCAAAAAAGGCAAACGGCGGCGGGCTGGATATATACGTAGACAAAAGCCGCGACAATTCGCC
CATTTACAAATTGAAGGATCATCCTTGGTTGGGCGTGTCTTTCAATTTGAGCGCCAAGGGTACCGCCAACGATGGTAAGA
CAATCAACAAATTTGATGAAAAGAATAGTAATAACAACCTCGTCTATACCACGGAAAGCCACCCTATTTCCCTTGGCGAC
GGGCAGCGCGAACATACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAAAGATAT
CACCGACAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGCGGCAGCGGCAAGGTGCCGGCTGGCTAAATT
TTTGGGCTAAGTGGGACATTAAAGATAACGGGCAGATTCCAGTCAAGCTCGGCCTGCAGCAAGTCAAAGCAGGCCGCTGC
ATCACCACACCGAACCCCAATCCCAAATCCAAAGCCCTTTCGCCGGCCCTGACTGCCCCCGCGCTGTGGTTCGGACCTGT
GCAAAATGGTAAGGCGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCCAAATTTTCCTGCAAA
ACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATTAAAAGTAAA
GAGCCGAGTTTCACGGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACGGCATATCCAACTGGATAGAAACAATGA
GGCCACCGGTTTTAATGGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAAGGAATATAGCGTCAATCCTGAGACCA
ATGAGTGGAAAAAGGTGCTGCTGCCTTGGACGGTTCGGGGTTTTAGTAATGACAATGAATTTGCAAAATTCAACAAAAAA
TCAGACAAATACAGCCAAAGATACCGCATCCGCGACAACAACGGCAATCGCAATTTGGGCGACATCGTCAACAGCCCCAT
CGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGC
GCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATTGAAAGCAAAGACTCCAACCTCGCC
AAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGTGGCTTTGTCTTGCGCCAAGT
CGAATGGAAAGGGCAAAACCGCGTGTTTATGTTTGGCGCGATGGGCTTTGGCGGCAGAGGCGCATACGCCTTGGATTTGA
CCAAAGCCGACGGCAGTGACCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAATAGTGGCAAGAATAGCAATAAT
AGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAAATACGCCGCCTT
CCTCGCCTCCGGTTATGCGACTAAACAGATTGACAGCGCAGACAATAAAACCGCGCTGTATGTATATGATTTGGAAAGCA
GCGGCAATTTGATTAAAAAAATCGAAGTACCCAACGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTG
GACGGCACGGTTGATATCGCCTATGCCGGCGATCGCGGCGGCAGTATGTATCGCTTTGATTTGAGCGGCAACGACCCGAC
CAAATGGTCTGCACGCGCCATTTTCAGCGGCAACAAACCGATTACTTCCGCGCCCGCTATTTCCCAACTGAAAGACAAAC
GCGTGGTTATCTTCGGTACGGGCAGCGATTTGAGTGAAGAGGATGTTGATAATAATGATATGCAATCTATTTACGGTATT
TTTGACAACGATACGGCGGCGGGTAATGCAAATGCAAACCTCAGCGGTTTGGGAGGCGGGCTGCTCGAGCAAAAGCTTAC
TCAGGAGGATAGAACCTTATTCCTGACCGATTACAAGCGATCCGACGGATCGGGCAGTAAGGGATGGGTAGTGAACTTGC
AGCCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAAAGACAAC
GGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGAT
TGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGCCATAAGAAAGAAAACGGCAAATCCATCCCTATAGGTTGTA
TGTGGAAAAACAATGAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAG
AAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAA
AAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGA
TGTGCGGTATGAAACGAATCAGCTGGCGCGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(499-836)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

78.415

100

0.799

Multiple sequence alignment