Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV167_RS08320 Genome accession   NZ_CP031329
Coordinates   1425766..1426626 (+) Length   286 a.a.
NCBI ID   WP_002251040.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22425     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1420766..1431626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV167_RS08295 dapD 1421276..1422097 (-) 822 WP_002224875.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  DV167_RS08300 - 1422107..1422337 (-) 231 WP_025462714.1 hypothetical protein -
  DV167_RS08305 pgi 1422307..1423950 (-) 1644 WP_002251041.1 glucose-6-phosphate isomerase -
  DV167_RS08315 pilG 1424460..1425692 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  DV167_RS08320 pilD 1425766..1426626 (+) 861 WP_002251040.1 A24 family peptidase Machinery gene
  DV167_RS08325 coaE 1426628..1427260 (+) 633 WP_002251039.1 dephospho-CoA kinase -
  DV167_RS08330 - 1427253..1427462 (+) 210 WP_002212333.1 DNA gyrase inhibitor YacG -
  DV167_RS08335 pilF 1427547..1429223 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DV167_RS08355 - 1429715..1430161 (-) 447 WP_002233503.1 DUF441 domain-containing protein -
  DV167_RS08360 ispB 1430166..1431140 (-) 975 WP_002216396.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31329.37 Da        Isoelectric Point: 8.4690

>NTDB_id=305792 DV167_RS08320 WP_002251040.1 1425766..1426626(+) (pilD) [Neisseria meningitidis strain M22425]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAR
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=305792 DV167_RS08320 WP_002251040.1 1425766..1426626(+) (pilD) [Neisseria meningitidis strain M22425]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAGCGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGCGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.789

99.65

0.955
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

45.29

96.503

0.437
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment