Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   DV144_RS02340 Genome accession   NZ_CP031328
Coordinates   377082..378347 (+) Length   421 a.a.
NCBI ID   WP_002238541.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18755     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 372082..383347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV144_RS02315 - 372812..373813 (+) 1002 WP_002223261.1 thiamine ABC transporter substrate-binding protein -
  DV144_RS02320 - 373907..374755 (+) 849 WP_002215243.1 mechanosensitive ion channel family protein -
  DV144_RS02325 - 374781..375266 (+) 486 WP_002221794.1 CinA family protein -
  DV144_RS02330 msrAB 375368..376936 (-) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  DV144_RS02340 pilA 377082..378347 (+) 1266 WP_002238541.1 signal recognition particle-docking protein FtsY Machinery gene
  DV144_RS02355 - 379136..379420 (+) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  DV144_RS14310 pilC 380840..380965 (+) 126 WP_324186162.1 hypothetical protein Machinery gene

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45231.53 Da        Isoelectric Point: 4.5585

>NTDB_id=305722 DV144_RS02340 WP_002238541.1 377082..378347(+) (pilA) [Neisseria meningitidis strain M18755]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GESIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=305722 DV144_RS02340 WP_002238541.1 377082..378347(+) (pilA) [Neisseria meningitidis strain M18755]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTAGAGAAACCGCTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCTGGCATCAACGGCGCGGGCAAAACCACATCCATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCACTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAAGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(221-420)

SRP54-type protein, helical bundle domain (SRP54_N)

(136-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

94.299

100

0.943

Multiple sequence alignment