Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV144_RS00080 Genome accession   NZ_CP031328
Coordinates   13449..16559 (+) Length   1036 a.a.
NCBI ID   WP_115430664.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18755     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 8449..21559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV144_RS00045 hpaC 8736..9236 (-) 501 WP_101042283.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV144_RS00050 nadR 9351..9791 (-) 441 WP_115430663.1 MarR family adhesin repressor NadR -
  DV144_RS00060 - 10134..10643 (-) 510 WP_002249078.1 protein disulfide oxidoreductase -
  DV144_RS00070 apbC 11013..12092 (+) 1080 WP_101126242.1 iron-sulfur cluster carrier protein ApbC -
  DV144_RS14220 pilC 13289..13414 (+) 126 WP_275895500.1 hypothetical protein Machinery gene
  DV144_RS00080 pilC 13449..16559 (+) 3111 WP_115430664.1 PilC family type IV pilus tip adhesin Machinery gene
  DV144_RS00105 carA 17959..19092 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV144_RS00110 - 19146..19283 (+) 138 WP_002243840.1 VOC family protein -
  DV144_RS00120 - 19844..20233 (+) 390 WP_002219820.1 endonuclease domain-containing protein -
  DV144_RS00125 - 20810..21373 (+) 564 WP_002214615.1 phosphoribosyltransferase family protein -

Sequence

Protein


Download         Length: 1036 a.a.        Molecular weight: 113290.11 Da        Isoelectric Point: 9.8512

>NTDB_id=305716 DV144_RS00080 WP_115430664.1 13449..16559(+) (pilC) [Neisseria meningitidis strain M18755]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAQAQTRQYAIIMNEGNQPEVQWNGSYSIKDKDRKREYTHHNHSRGGSSVS
FNNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADGLNKRGNAAGWIRTTRIALAGYSYEGVVCRSGTGCPKLVYKTRFS
FDNPDLVKNAGRLDRHTDPSRENSPIYKLKDYPWLGVSFNLGAEGTTKDGKTINKLVSSFDEKNSSNNNLVYTTEGRDIS
LGDWQREKTAMAYYLNAKLHLLDKKGIKDITNKTVQLGVLRPSIDVRLQRNTGLAGLLNFWASWDIKDNGQIPVKLGLPE
VKAGRCINANNPNKSTKAPSPALTAPALWFGPVQNGKMEMYSASVSTYPDSSSSRIFLQNLKRKNDPNKPGRYSLADLSA
SEIKSREPNFTGRQTIIRLNGGVREIKLDRNNTEVVNFNGNDGNNATFGIVSEGSFMPDDSEWKKVLLPWTVRGVNDDQF
KTFNKEEKNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGDARNYSLKLSYIPGTMPR
KDIQNTESTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLSKIDSNNPTAVSLFD
VKHDNNGKNSNNGVKLGYTVGTPQIGKTHDGKYAAFLASGYATKDITSGDNKTALYVYDLESSGTLIKKIDVPGGKGGLS
SPTLVDKDLDGTVDIAYAGDRGGKMYRFDLSGNNPNSWTVRTIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDN
KDIQHVYGIFDNDTDTSVAKDGQGNGLLEQVLSRDNDNKTLFLTDYKRSNGSGSKGWMVKLQPGQRVTVKPTVVLRTAFV
TIRKYTTDGCGAETAILGINTADGGKLTKKSARPIVPEANSKVAQYSGDKKTSSGKSIPIGCMEKDNGIVCPNGYVYDKP
VNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRAGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3111 bp        

>NTDB_id=305716 DV144_RS00080 WP_115430664.1 13449..16559(+) (pilC) [Neisseria meningitidis strain M18755]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGCAGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTACAGTGGAATG
GGTCATATTCAATAAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACTCACGAGGAGGAAGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGGGCTGAACAAGCGCGGCAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGTAAAAAATGCGGGCAGGCTGGATAGGCACACAGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGTGCCGAGGGTACCACCAAAGATGGTAAGACAATCA
ACAAATTGGTATCTTCTTTTGATGAAAAGAATAGTAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCC
TTGGGCGACTGGCAGCGCGAAAAGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGAT
TAAAGATATCACCAACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGCGGCTGCAAAGAAATACGGGGC
TTGCCGGCTTGCTAAATTTTTGGGCTAGTTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAA
GTCAAAGCAGGCCGCTGCATCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACTGCCCCCGC
GCTGTGGTTCGGACCTGTGCAAAATGGTAAGATGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCA
GCCGCATCTTCCTTCAAAATCTGAAAAGAAAAAACGACCCCAACAAACCCGGCCGCTATTCCCTCGCAGACTTGAGCGCG
TCGGAGATTAAAAGTCGAGAGCCGAATTTCACAGGGCGGCAAACCATCATCCGATTGAATGGCGGCGTACGTGAGATCAA
ACTGGATAGAAACAATACTGAGGTCGTCAATTTTAATGGAAATGACGGCAACAACGCAACTTTCGGCATTGTTAGTGAAG
GGAGCTTCATGCCTGATGACAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTGTCAATGACGATCAATTT
AAAACATTCAACAAAGAAGAAAAAAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGA
GCGCAATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGG
TGCATATCTTCAAAAAAGGCAACGGGGACGCGCGCAACTATAGTCTGAAGCTCAGTTATATCCCGGGCACGATGCCGCGC
AAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTA
CGGCGTGGACGGCGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCGGCGCGATGG
GCTTTGGCGGCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGAT
GTCAAACATGACAATAATGGCAAGAATAGCAATAACGGCGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAA
AACCCACGACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGACATTACCAGCGGCGACAATAAAACCG
CGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCG
TCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAAGATGTACCG
CTTTGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCACTATTTTTGAAGGTACAAAACCGATTACTTCCGCGC
CCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGAAGATGTGGACAAC
AAAGACATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACAAGTGTGGCGAAAGACGGGCAGGGCAACGGGCT
GCTCGAGCAAGTGCTTAGTAGGGATAACGACAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCA
GTAAGGGGTGGATGGTGAAATTGCAGCCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTA
ACCATCCGCAAATATACCACCGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCT
GACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATTCGAAGGTCGCGCAATATTCCGGCGATAAGAAAACTTCCA
GCGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCG
GTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTAT
AGACCCCGCCGGCAAGCGTGCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATT
TGGACAGCTTGGATATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(510-844)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

80.115

100

0.809

Multiple sequence alignment