Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA02_RS21950 Genome accession   NZ_CP035841
Coordinates   4497433..4498089 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TW10722     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4492433..4503089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA02_RS21920 dcyD 4493313..4494299 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  EXA02_RS21925 tcyL 4494314..4494982 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA02_RS21930 tcyN 4494979..4495731 (+) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA02_RS21935 sdiA 4495961..4496683 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  EXA02_RS21940 yecF 4496750..4496974 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA02_RS21945 yecU 4496961..4497137 (-) 177 WP_000590347.1 protein YecU -
  EXA02_RS28805 - 4497220..4497291 (-) 72 Protein_4318 transcriptional regulator -
  EXA02_RS21950 letA 4497433..4498089 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA02_RS21955 uvrC 4498086..4499918 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA02_RS21960 pgsA 4499975..4500523 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA02_RS21980 - 4501517..4501798 (+) 282 WP_071595684.1 hypothetical protein -
  EXA02_RS21985 - 4501988..4502128 (-) 141 WP_000078920.1 Hok/Gef family protein -
  EXA02_RS21990 - 4502318..4502578 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305685 EXA02_RS21950 WP_000611335.1 4497433..4498089(+) (letA) [Escherichia coli strain TW10722]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305685 EXA02_RS21950 WP_000611335.1 4497433..4498089(+) (letA) [Escherichia coli strain TW10722]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment