Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV175_RS05710 Genome accession   NZ_CP031324
Coordinates   962927..966049 (-) Length   1040 a.a.
NCBI ID   WP_115437375.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M23347     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 957927..971049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV175_RS05655 - 958675..959064 (-) 390 WP_002238353.1 endonuclease domain-containing protein -
  DV175_RS05665 carA 959808..960941 (-) 1134 WP_002238352.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV175_RS13660 - 961127..961540 (-) 414 WP_162818900.1 hypothetical protein -
  DV175_RS05710 pilC 962927..966049 (-) 3123 WP_115437375.1 PilC family type IV pilus tip adhesin Machinery gene
  DV175_RS05720 apbC 966851..967930 (-) 1080 WP_024465095.1 iron-sulfur cluster carrier protein ApbC -
  DV175_RS05730 - 968295..968804 (+) 510 WP_002233029.1 protein disulfide oxidoreductase -
  DV175_RS05740 nadR 969145..969585 (+) 441 Protein_927 MarR family adhesin repressor NadR -
  DV175_RS05745 hpaC 969700..970200 (+) 501 WP_024465094.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV175_RS05750 murU 970218..970913 (+) 696 WP_002237354.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1040 a.a.        Molecular weight: 113553.39 Da        Isoelectric Point: 9.6395

>NTDB_id=305602 DV175_RS05710 WP_115437375.1 962927..966049(-) (pilC) [Neisseria meningitidis strain M23347]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGAMAQTRQYAIIMNEGNQPEVQWNGSYSIKDKDRKREYTHHNHQQGGSSVS
FNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDAAALKERNNAVDWIHTTHPGLIGYSYDGVVCRSATDCPKLVYKTRFS
FDNPDLAKTGGGLDRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGAAKNGKTINKLVSSFDEKNKNSNNNLVYTTEGRDI
SLGDWQRESTAMAYYLNAKLHLLDKKQIQNITDKTVQLGVLRPSIDVKTQKTGLAGILAYWARWDIKDDGQIPVKLGLQQ
VKAGRCVNKNNPNPNAKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSA
SDIQSKEPNFTGRQTIIRLDGGVREIKLNRSNEATGLNGNDGKNETFGIVSEGSFMPDTSEWKKVLLPWTVRGFADDSKF
KEFNKEEKNNDNKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGGYLATSANDGMVHIFKKGNGGDERNYSLKLSYIPGT
MPRKNIENNDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLTKADSNNPTAVS
LFDVKNDKNSNNGVELGYTVGTPQIGKTHNGKYAAFLASGYATKEITSGDNKTALYVYDLEGNGTNNLIKKIEVPGGKGG
LSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSSQDPKQWSARAIFKGDKPITSAPAISQLKDKRVVIFGTGSDLSEDDV
LSTSEQYIYGIFDDDTAASNVDVKLKGLGGGLLEQVLEQKDKTLFLTDYKRSDGSGNKGWVVKLKDGQRVTVKPTVVLRT
AFVTIHKYTGTDKCGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKKTANGKSIPIGCMQKGNETVCPNGYV
YDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPMCGMKRISWREVFF

Nucleotide


Download         Length: 3123 bp        

>NTDB_id=305602 DV175_RS05710 WP_115437375.1 962927..966049(-) (pilC) [Neisseria meningitidis strain M23347]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTACAGTGGAATG
GGTCATATTCAATAAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACCAACAAGGAGGAAGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGCCGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCACCCAGGGT
TGATAGGCTACAGCTACGACGGTGTCGTATGCAGAAGCGCCACAGACTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGCAAAAACAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGTGCCGAGGGTGCCGCCAAAAATGGTAAGACAATCA
ACAAATTGGTATCTTCTTTTGATGAAAAGAATAAGAATAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATT
TCCTTGGGCGACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACA
GATTCAAAATATCACCGACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGAAGACACAAAAGACGGGGC
TTGCCGGCATTCTAGCTTATTGGGCTAGGTGGGACATTAAAGATGACGGGCAGATTCCAGTCAAGCTCGGCCTGCAGCAA
GTCAAAGCAGGCCGCTGCGTCAACAAAAATAACCCCAATCCCAATGCCAAAGCCCCTTCGCCGGCACTGACTGCCCCCGC
GCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCA
GCCAAATTTTCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTGCG
TCGGATATTCAAAGTAAAGAGCCGAATTTCACGGGGCGGCAAACAATCATCCGATTGGATGGCGGCGTACGTGAGATCAA
ACTGAATAGAAGCAATGAGGCCACCGGTTTAAATGGAAATGACGGCAAAAACGAAACTTTCGGCATTGTTAGCGAAGGGA
GCTTCATGCCTGATACCAGCGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGGGGTTTTGCTGATGACAGTAAATTT
AAAGAATTCAACAAAGAAGAAAAAAACAACGACAACAAGCCAAAATACAGCCAAAAATACCGCAGCCGCGACAACGGCAA
GCACGAGCGCAATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCTACTTCCGCCAACGACG
GGATGGTGCATATCTTCAAAAAAGGCAACGGCGGGGACGAGCGCAACTATAGTCTGAAGCTCAGTTATATCCCGGGCACG
ATGCCGCGCAAGAATATTGAAAACAACGACTCCACCCTCGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGG
CGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCG
GCGCGATGGGCTTTGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCC
CTGTTTGATGTCAAAAATGACAAGAATAGCAATAACGGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAA
AACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGAAATTACCAGCGGCGACAATAAAACCG
CGCTGTATGTGTATGATTTGGAAGGAAACGGTACGAATAATCTGATTAAAAAAATCGAAGTACCCGGTGGCAAGGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATAT
GTACCGCTTTGATTTGAGCAGTCAAGATCCTAAACAATGGTCTGCACGCGCCATTTTTAAAGGCGACAAACCGATTACTT
CCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTA
CTCAGTACGAGCGAACAATATATTTACGGTATCTTCGACGACGATACGGCGGCGAGTAATGTAGATGTAAAACTCAAAGG
TTTGGGAGGCGGGTTGCTCGAGCAGGTGCTTGAGCAGAAGGATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACG
GATCGGGCAATAAGGGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAGCCGACCGTGGTATTGCGTACC
GCCTTTGTAACCATCCATAAATATACGGGTACGGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGA
CGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCGGTCATA
AGAAAACCGCCAACGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAACCGTCTGCCCGAACGGATATGTT
TACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGG
CGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGC
TGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGATGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTC
TGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(512-847)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

80.325

100

0.809

Multiple sequence alignment