Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV175_RS03240 Genome accession   NZ_CP031324
Coordinates   574039..574485 (-) Length   148 a.a.
NCBI ID   WP_025462628.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M23347     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 565630..580717 574039..574485 within 0


Gene organization within MGE regions


Location: 565630..580717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV175_RS03200 dcm 565630..566460 (+) 831 WP_002215283.1 DNA (cytosine-5-)-methyltransferase -
  DV175_RS14535 - 566438..566632 (+) 195 WP_002215282.1 DNA cytosine methyltransferase -
  DV175_RS03205 - 566625..566969 (+) 345 WP_002228843.1 DNA adenine methylase -
  DV175_RS03210 galE 567048..567668 (+) 621 Protein_531 UDP-glucose 4-epimerase GalE -
  DV175_RS03215 rfbB 567784..568851 (+) 1068 WP_101132117.1 dTDP-glucose 4,6-dehydratase -
  DV175_RS03220 rfbA 568914..569780 (+) 867 WP_061728352.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DV175_RS03225 rfbC 569834..570391 (+) 558 WP_002237508.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  DV175_RS03230 - 570435..572453 (-) 2019 WP_002237507.1 oligopeptide transporter, OPT family -
  DV175_RS03235 dnaJ 572649..573770 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  DV175_RS14010 - 573852..574010 (-) 159 WP_002215272.1 hypothetical protein -
  DV175_RS03240 comE 574039..574485 (-) 447 WP_025462628.1 ComEA family DNA-binding protein Machinery gene
  DV175_RS03280 dksA 580301..580717 (-) 417 WP_002231430.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 148 a.a.        Molecular weight: 15857.88 Da        Isoelectric Point: 10.8359

>NTDB_id=305593 DV175_RS03240 WP_025462628.1 574039..574485(-) (comE) [Neisseria meningitidis strain M23347]
MSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCTFSLAAVNINAASQQEL
EALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 447 bp        

>NTDB_id=305593 DV175_RS03240 WP_025462628.1 574039..574485(-) (comE) [Neisseria meningitidis strain M23347]
ATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTTGAAACTTTGGGATATTCA
TTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAAAAACCATGAAGAAAATGT
TCGTGCTGTTCTGTATGCTGTTCTCCTGCACCTTCTCCCTTGCGGCGGTAAACATCAATGCGGCTTCGCAGCAGGAGTTG
GAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAACGGTGCGTTCAAGTCTGT
AGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGGCTTCTGTCGGCGCGCCCG
CACCAAAAGGCCCAGCCAAACCGGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(69-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

82.432

0.77
  comE Neisseria gonorrhoeae MS11

93.443

82.432

0.77
  comE Neisseria gonorrhoeae MS11

93.443

82.432

0.77
  comE Neisseria gonorrhoeae MS11

93.443

82.432

0.77

Multiple sequence alignment