Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA03_RS05845 Genome accession   NZ_CP035836
Coordinates   1136319..1136975 (-) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain WS1933D     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1131319..1141975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA03_RS05815 yecA 1132570..1133235 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  EXA03_RS05835 pgsA 1133885..1134433 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA03_RS05840 uvrC 1134490..1136322 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA03_RS05845 letA 1136319..1136975 (-) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA03_RS05850 yecU 1137271..1137447 (+) 177 WP_001307856.1 protein YecU -
  EXA03_RS05855 yecF 1137434..1137658 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA03_RS05860 sdiA 1137725..1138447 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  EXA03_RS05865 tcyN 1138677..1139429 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA03_RS05870 tcyL 1139426..1140094 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA03_RS05875 dcyD 1140109..1141095 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305532 EXA03_RS05845 WP_000611338.1 1136319..1136975(-) (letA) [Escherichia coli strain WS1933D]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305532 EXA03_RS05845 WP_000611338.1 1136319..1136975(-) (letA) [Escherichia coli strain WS1933D]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491