Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA04_RS10325 Genome accession   NZ_CP035832
Coordinates   2125235..2125891 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 025542-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120235..2130891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA04_RS10295 dcyD 2121115..2122101 (+) 987 WP_001128227.1 D-cysteine desulfhydrase -
  EXA04_RS10300 tcyL 2122116..2122784 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA04_RS10305 tcyN 2122781..2123533 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA04_RS10310 sdiA 2123763..2124485 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  EXA04_RS10315 yecF 2124552..2124776 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA04_RS10320 yecU 2124763..2124939 (-) 177 WP_000590344.1 protein YecU -
  EXA04_RS26720 - 2124977..2125093 (-) 117 WP_001302039.1 hypothetical protein -
  EXA04_RS10325 letA 2125235..2125891 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA04_RS10330 uvrC 2125888..2127720 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA04_RS10335 pgsA 2127777..2128325 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA04_RS10355 yecA 2128975..2129640 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=305478 EXA04_RS10325 WP_000611328.1 2125235..2125891(+) (letA) [Escherichia coli strain 025542-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305478 EXA04_RS10325 WP_000611328.1 2125235..2125891(+) (letA) [Escherichia coli strain 025542-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482