Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA05_RS24370 Genome accession   NZ_CP035826
Coordinates   4988966..4989622 (-) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain 67-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4983966..4994622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA05_RS24340 yecA 4985217..4985882 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  EXA05_RS24360 pgsA 4986532..4987080 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA05_RS24365 uvrC 4987137..4988969 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA05_RS24370 letA 4988966..4989622 (-) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA05_RS24375 yecU 4989918..4990094 (+) 177 WP_001307856.1 protein YecU -
  EXA05_RS24380 yecF 4990081..4990305 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA05_RS24385 sdiA 4990372..4991094 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  EXA05_RS24390 tcyN 4991324..4992076 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA05_RS24395 tcyL 4992073..4992741 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA05_RS24400 dcyD 4992756..4993742 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305439 EXA05_RS24370 WP_000611338.1 4988966..4989622(-) (letA) [Escherichia coli strain 67-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305439 EXA05_RS24370 WP_000611338.1 4988966..4989622(-) (letA) [Escherichia coli strain 67-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491

Multiple sequence alignment