Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   DWB98_RS09165 Genome accession   NZ_CP031275
Coordinates   1940052..1940615 (-) Length   187 a.a.
NCBI ID   WP_017722273.1    Uniprot ID   A0A2T4PJ80
Organism   Staphylococcus xylosus strain     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1932477..1939559 1940052..1940615 flank 493


Gene organization within MGE regions


Location: 1932477..1940615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWB98_RS13670 - 1933389..1933517 (-) 129 WP_261376911.1 hypothetical protein -
  DWB98_RS09115 (DWB98_09130) - 1933527..1933718 (-) 192 WP_107543217.1 hypothetical protein -
  DWB98_RS09120 (DWB98_09135) - 1933811..1934335 (-) 525 WP_107543218.1 hypothetical protein -
  DWB98_RS09125 (DWB98_09140) - 1934466..1934897 (-) 432 WP_107543219.1 hypothetical protein -
  DWB98_RS09130 (DWB98_09145) - 1935035..1935895 (-) 861 WP_107543220.1 hypothetical protein -
  DWB98_RS09135 (DWB98_09150) - 1935971..1937398 (-) 1428 WP_261376912.1 SH3 domain-containing protein -
  DWB98_RS09140 (DWB98_09155) - 1937304..1937663 (+) 360 WP_145511737.1 DUF4352 domain-containing protein -
  DWB98_RS09145 (DWB98_09160) - 1937717..1938247 (+) 531 WP_107543046.1 hypothetical protein -
  DWB98_RS09150 (DWB98_09165) - 1938528..1939559 (+) 1032 WP_241959992.1 site-specific integrase -
  DWB98_RS09165 (DWB98_09180) comK/comK1 1940052..1940615 (-) 564 WP_017722273.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 187 a.a.        Molecular weight: 21879.23 Da        Isoelectric Point: 9.5361

>NTDB_id=305363 DWB98_RS09165 WP_017722273.1 1940052..1940615(-) (comK/comK1) [Staphylococcus xylosus strain]
MIQPYIIKKGDMVLQPCNLATGQYEGSYLLRYKADSQIIKERVSKIIDRSCRFYGSSYVFKKEDTMRITGISSKPPILFT
PLFPTYFFPTHSDRKADNTWINIHYVHNIRPLKEKKCKVTFVDNQSIVANISAHSMHHQYLNGIYYYYMMDRAARVATFD
PDSPIDYTKPQLNIYEALAKYSLFESK

Nucleotide


Download         Length: 564 bp        

>NTDB_id=305363 DWB98_RS09165 WP_017722273.1 1940052..1940615(-) (comK/comK1) [Staphylococcus xylosus strain]
ATGATTCAACCGTATATTATTAAAAAAGGTGATATGGTTTTACAACCATGTAATTTAGCTACTGGACAATATGAAGGTAG
TTACTTGCTAAGGTATAAAGCTGACAGTCAAATTATTAAAGAACGAGTATCTAAAATCATCGACCGTTCATGTAGGTTTT
ATGGTAGCAGTTATGTATTTAAAAAAGAAGATACCATGCGTATTACAGGCATAAGCAGTAAGCCACCTATTCTATTCACT
CCATTATTTCCCACTTATTTCTTTCCCACACACTCTGATCGTAAAGCAGATAATACCTGGATTAATATCCATTATGTACA
TAATATTAGACCACTTAAAGAAAAGAAATGTAAGGTTACCTTTGTAGATAATCAAAGTATTGTAGCTAACATTTCTGCTC
ATAGTATGCATCATCAATATTTAAATGGTATATATTATTATTACATGATGGATAGGGCAGCTAGAGTCGCTACATTTGAT
CCTGATTCACCGATTGATTATACTAAACCACAATTAAATATATATGAAGCATTGGCTAAATATTCGTTGTTTGAATCGAA
ATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(4-152)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4PJ80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

55.738

97.861

0.545
  comK/comK1 Staphylococcus aureus N315

55.738

97.861

0.545

Multiple sequence alignment