Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA06_RS07230 Genome accession   NZ_CP035822
Coordinates   1445782..1446438 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain WS4437A-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1440782..1451438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA06_RS07200 yecA 1442035..1442699 (-) 665 Protein_1422 UPF0149 family protein YecA -
  EXA06_RS07220 pgsA 1443348..1443896 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA06_RS07225 uvrC 1443953..1445785 (-) 1833 WP_001413419.1 excinuclease ABC subunit UvrC Machinery gene
  EXA06_RS07230 letA 1445782..1446438 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA06_RS24955 - 1446580..1446696 (+) 117 WP_001302039.1 hypothetical protein -
  EXA06_RS07235 yecU 1446734..1446910 (+) 177 WP_000590344.1 protein YecU -
  EXA06_RS07240 yecF 1446897..1447121 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA06_RS07245 sdiA 1447189..1447911 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  EXA06_RS07250 tcyN 1448141..1448893 (-) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA06_RS07255 tcyL 1448890..1449558 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA06_RS07260 dcyD 1449573..1450559 (-) 987 WP_001128227.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305289 EXA06_RS07230 WP_000611335.1 1445782..1446438(-) (letA) [Escherichia coli strain WS4437A-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305289 EXA06_RS07230 WP_000611335.1 1445782..1446438(-) (letA) [Escherichia coli strain WS4437A-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486