Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DWB87_RS02605 Genome accession   NZ_CP031265
Coordinates   539803..540372 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain 13     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 534803..545372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWB87_RS02580 (DWB87_02640) cysE 536016..536663 (+) 648 WP_011382202.1 serine O-acetyltransferase -
  DWB87_RS02585 (DWB87_02645) cysS 536647..538047 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  DWB87_RS02590 (DWB87_02650) - 538040..538444 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  DWB87_RS02595 (DWB87_02655) rlmB 538452..539198 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DWB87_RS02600 (DWB87_02660) - 539198..539722 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DWB87_RS02605 (DWB87_02665) sigH 539803..540372 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  DWB87_RS02610 (DWB87_02670) rpmG 540487..540630 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DWB87_RS02615 (DWB87_02675) secE 540686..540868 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DWB87_RS02620 (DWB87_02680) nusG 540881..541429 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DWB87_RS02625 (DWB87_02685) rplK 541610..542032 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DWB87_RS02630 (DWB87_02690) rplA 542240..542932 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DWB87_RS02640 (DWB87_02700) rplJ 543204..543704 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  DWB87_RS02645 (DWB87_02705) rplL 543747..544115 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DWB87_RS02650 (DWB87_02710) - 544290..544898 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=305211 DWB87_RS02605 WP_000872877.1 539803..540372(+) (sigH) [Staphylococcus aureus strain 13]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=305211 DWB87_RS02605 WP_000872877.1 539803..540372(+) (sigH) [Staphylococcus aureus strain 13]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment