Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA07_RS03425 Genome accession   NZ_CP035819
Coordinates   696327..696983 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain WS3294A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 691327..701983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA07_RS03395 yecA 692578..693243 (-) 666 WP_000847876.1 UPF0149 family protein YecA -
  EXA07_RS03415 pgsA 693893..694441 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA07_RS03420 uvrC 694498..696330 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA07_RS03425 letA 696327..696983 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA07_RS25915 - 697125..697241 (+) 117 WP_001302039.1 hypothetical protein -
  EXA07_RS03430 yecU 697279..697455 (+) 177 WP_000590344.1 protein YecU -
  EXA07_RS03435 yecF 697442..697666 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA07_RS03440 sdiA 697733..698455 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  EXA07_RS03445 tcyN 698685..699437 (-) 753 WP_001373919.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA07_RS03450 tcyL 699434..700102 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA07_RS03455 dcyD 700117..701103 (-) 987 WP_001373912.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=305196 EXA07_RS03425 WP_000611328.1 696327..696983(-) (letA) [Escherichia coli strain WS3294A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305196 EXA07_RS03425 WP_000611328.1 696327..696983(-) (letA) [Escherichia coli strain WS3294A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482