Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA08_RS11420 Genome accession   NZ_CP035817
Coordinates   2330088..2330744 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E7476     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2325088..2335744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA08_RS11390 dcyD 2325968..2326954 (+) 987 WP_025652951.1 D-cysteine desulfhydrase -
  EXA08_RS11395 tcyL 2326969..2327637 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXA08_RS11400 tcyN 2327634..2328386 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXA08_RS11405 sdiA 2328616..2329338 (+) 723 WP_001154275.1 transcriptional regulator SdiA -
  EXA08_RS11410 yecF 2329405..2329629 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXA08_RS11415 yecU 2329616..2329792 (-) 177 WP_032160694.1 protein YecU -
  EXA08_RS11420 letA 2330088..2330744 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXA08_RS11425 uvrC 2330741..2332573 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXA08_RS11430 pgsA 2332630..2333178 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXA08_RS11450 yecA 2333828..2334493 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=305156 EXA08_RS11420 WP_000611328.1 2330088..2330744(+) (letA) [Escherichia coli strain E7476]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305156 EXA08_RS11420 WP_000611328.1 2330088..2330744(+) (letA) [Escherichia coli strain E7476]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment