Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   DV130_RS09825 Genome accession   NZ_CP031248
Coordinates   1822656..1823276 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain M26365     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1817656..1828276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS09795 - 1817690..1818322 (-) 633 WP_050072293.1 ABC transporter ATP-binding protein -
  DV130_RS09800 - 1818324..1820339 (-) 2016 WP_050072292.1 DUF1430 domain-containing protein -
  DV130_RS09805 - 1820442..1820738 (-) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  DV130_RS12795 - 1821053..1821222 (-) 170 Protein_1849 PhrA family quorum-sensing system peptide -
  DV130_RS09815 - 1821410..1822273 (+) 864 WP_001093628.1 helix-turn-helix transcriptional regulator -
  DV130_RS09825 comM 1822656..1823276 (+) 621 WP_000839908.1 hypothetical protein Regulator
  DV130_RS09830 tsaE 1823362..1823805 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  DV130_RS09835 - 1823795..1824313 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  DV130_RS09840 - 1824321..1825337 (+) 1017 WP_000239282.1 LCP family protein -
  DV130_RS09845 cinA 1825421..1826677 (+) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  DV130_RS09850 recA 1826732..1827898 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=304877 DV130_RS09825 WP_000839908.1 1822656..1823276(+) (comM) [Streptococcus pneumoniae strain M26365]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=304877 DV130_RS09825 WP_000839908.1 1822656..1823276(+) (comM) [Streptococcus pneumoniae strain M26365]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment