Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DV130_RS05890 Genome accession   NZ_CP031248
Coordinates   1126967..1127656 (-) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain M26365     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1121967..1132656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS05870 - 1122560..1123435 (+) 876 WP_232035156.1 lanthionine synthetase LanC family protein -
  DV130_RS05875 - 1123502..1124710 (+) 1209 WP_224757090.1 MFS transporter -
  DV130_RS05880 cbpJ 1124829..1125827 (-) 999 WP_050088043.1 choline-binding protein CbpJ -
  DV130_RS05885 cbpC 1125846..1126868 (-) 1023 WP_000771051.1 choline-binding protein CbpC -
  DV130_RS05890 covR 1126967..1127656 (-) 690 WP_000518008.1 response regulator transcription factor Regulator
  DV130_RS05895 gndA 1127668..1129092 (-) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  DV130_RS05900 mapZ 1129168..1130562 (-) 1395 WP_023396578.1 mid-cell-anchored protein MapZ -
  DV130_RS05905 - 1130575..1131732 (-) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  DV130_RS05915 gpsB 1132218..1132547 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=304842 DV130_RS05890 WP_000518008.1 1126967..1127656(-) (covR) [Streptococcus pneumoniae strain M26365]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=304842 DV130_RS05890 WP_000518008.1 1126967..1127656(-) (covR) [Streptococcus pneumoniae strain M26365]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment