Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DV130_RS00065 Genome accession   NZ_CP031248
Coordinates   10068..11300 (+) Length   410 a.a.
NCBI ID   WP_001863391.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5068..16300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS00035 - 5135..5812 (+) 678 WP_000221611.1 DnaD domain-containing protein -
  DV130_RS00040 tpiA 5910..6668 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  DV130_RS00045 lytC 6706..8211 (+) 1506 WP_075575672.1 choline binding-anchored murein hydrolase LytC -
  DV130_RS00050 - 8707..9225 (+) 519 WP_000229868.1 Dps family protein -
  DV130_RS00055 - 9355..9861 (+) 507 WP_000162444.1 dihydrofolate reductase -
  DV130_RS12035 - 9861..10031 (+) 171 WP_000442277.1 hypothetical protein -
  DV130_RS00065 clpX 10068..11300 (+) 1233 WP_001863391.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DV130_RS00070 yihA 11309..11896 (+) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DV130_RS00075 - 11907..12287 (+) 381 WP_001140412.1 RidA family protein -
  DV130_RS00080 rapZ 12339..13229 (+) 891 WP_000163033.1 RNase adapter RapZ -
  DV130_RS00085 - 13226..14203 (+) 978 WP_114865116.1 YvcK family protein -
  DV130_RS00090 whiA 14200..15111 (+) 912 WP_000011276.1 DNA-binding protein WhiA -
  DV130_RS00095 - 15145..16113 (-) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45740.31 Da        Isoelectric Point: 4.4775

>NTDB_id=304819 DV130_RS00065 WP_001863391.1 10068..11300(+) (clpX) [Streptococcus pneumoniae strain M26365]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDANSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=304819 DV130_RS00065 WP_001863391.1 10068..11300(+) (clpX) [Streptococcus pneumoniae strain M26365]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGCAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTAGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATTGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment