Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DV129_RS05980 Genome accession   NZ_CP031247
Coordinates   1115587..1116276 (-) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110587..1121276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS05945 - 1111260..1111382 (-) 123 Protein_1125 cell wall-binding protein -
  DV129_RS12635 - 1112252..1112590 (+) 339 Protein_1126 lanthionine synthetase LanC family protein -
  DV129_RS05965 - 1112490..1112960 (+) 471 WP_001844742.1 lanthionine synthetase LanC family protein -
  DV129_RS05970 - 1113120..1114352 (+) 1233 WP_000765670.1 MFS transporter -
  DV129_RS05975 cbpC 1114470..1115489 (-) 1020 WP_000771110.1 choline-binding protein CbpC -
  DV129_RS05980 covR 1115587..1116276 (-) 690 WP_000518018.1 response regulator transcription factor Regulator
  DV129_RS05985 gndA 1116288..1117712 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  DV129_RS05990 mapZ 1117788..1119182 (-) 1395 WP_000039273.1 mid-cell-anchored protein MapZ -
  DV129_RS05995 - 1119195..1120352 (-) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  DV129_RS06005 gpsB 1120838..1121167 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=304766 DV129_RS05980 WP_000518018.1 1115587..1116276(-) (covR) [Streptococcus pneumoniae strain M23734]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=304766 DV129_RS05980 WP_000518018.1 1115587..1116276(-) (covR) [Streptococcus pneumoniae strain M23734]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment