Detailed information NTG0304733

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DV131_RS10600
• Genome accession: NZ_CP031246
• Coordinates: 1986826..1988058 (-)
• Length: 410 a.a.
• NCBI ID: WP_000106346.1
• Uniprot ID: A0A064C077
• Organism: Streptococcus pneumoniae strain M26368
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1981826..1993058

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV131_RS10570	-	1982014..1982982 (+)	969	WP_000081003.1	NAD(P)/FAD-dependent oxidoreductase	-
DV131_RS10575	whiA	1983015..1983926 (-)	912	WP_000011306.1	DNA-binding protein WhiA	-
DV131_RS10580	-	1983923..1984900 (-)	978	WP_001231086.1	YvcK family protein	-
DV131_RS10585	rapZ	1984897..1985787 (-)	891	WP_000163035.1	RNase adapter RapZ	-
DV131_RS10590	-	1985839..1986219 (-)	381	WP_001140412.1	RidA family protein	-
DV131_RS10595	yihA	1986230..1986817 (-)	588	WP_000422599.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DV131_RS10600	clpX	1986826..1988058 (-)	1233	WP_000106346.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DV131_RS11610	-	1988090..1988260 (-)	171	WP_081543945.1	hypothetical protein	-
DV131_RS10610	-	1988260..1988766 (-)	507	WP_002205327.1	dihydrofolate reductase	-
DV131_RS10615	-	1988896..1989414 (-)	519	WP_044813102.1	Dps family protein	-
DV131_RS10620	-	1990026..1991372 (-)	1347	WP_001837384.1	IS1380-like element ISSpn5 family transposase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45798.35 Da
• Isoelectric Point: 4.4550

>NTDB_id=304733 DV131_RS10600 WP_000106346.1 1986826..1988058(-) (clpX) [Streptococcus pneumoniae strain M26368]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=304733 DV131_RS10600 WP_000106346.1 1986826..1988058(-) (clpX) [Streptococcus pneumoniae strain M26368]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTTGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

3D structure

• AlphaFold DB: A0A064C077

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.585	100	0.866
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.214	98.049	0.561