Detailed information NTG0030470

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: VCD_RS01130
• Genome accession: NC_012668
• Coordinates: 219589..222411 (+)
• Length: 940 a.a.
• NCBI ID: WP_000357696.1
• Uniprot ID: Q9KUW5
• Organism: Vibrio cholerae MJ-1236
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 214589..227411

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VCD_RS01110 (VCD_001225)	csrD	214783..216741 (-)	1959	WP_000216141.1	RNase E specificity factor CsrD	-
VCD_RS01115 (VCD_001226)	ssb	216919..217452 (-)	534	WP_000168289.1	single-stranded DNA-binding protein	Machinery gene
VCD_RS01120 (VCD_001227)	qstR	217744..218388 (+)	645	WP_001188316.1	LuxR C-terminal-related transcriptional regulator	Regulator
VCD_RS01125 (VCD_001228)	galU	218561..219433 (+)	873	WP_001920788.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
VCD_RS01130 (VCD_001229)	uvrA	219589..222411 (+)	2823	WP_000357696.1	excinuclease ABC subunit UvrA	Machinery gene
VCD_RS01135 (VCD_001230)	-	222476..224260 (+)	1785	WP_000212615.1	oligosaccharyltransferase	-
VCD_RS01140 (VCD_001231)	-	224339..225457 (-)	1119	WP_000155556.1	pyridoxal-phosphate-dependent aminotransferase family protein	-
VCD_RS01145 (VCD_001232)	lysC	225921..227276 (+)	1356	WP_000102995.1	lysine-sensitive aspartokinase 3	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 104327.86 Da
• Isoelectric Point: 6.4814

>NTDB_id=30470 VCD_RS01130 WP_000357696.1 219589..222411(+) (uvrA) [Vibrio cholerae MJ-1236]
MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG
EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD
GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML
TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI
SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG
PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV
SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES
RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD
PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH
GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN

Nucleotide

• Length: 2823 bp

>NTDB_id=30470 VCD_RS01130 WP_000357696.1 219589..222411(+) (uvrA) [Vibrio cholerae MJ-1236]
ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT
TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG
TCGAATCACTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCATATTGAGGGGCTTTCA
CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACGATTACGGAAGTGTATGACTA
TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGCCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC
AGATGGTAGACAAAGTATTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC
GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC
CGATCCACCGAAACTCGAACTGCACAAAAAGCATACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC
AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTGGAACTTTCCGGCGGTATCGTCGTTGTCGCCCCGATGGAAGGCGAT
GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAACTTGAACCACGCCTGTT
CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA
TTCAAGATGCCAATTTAAGTTTGGCACAAGGTGCGATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG
ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACGCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT
GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTTAAAAAACATCCTTTTG
AAGGAATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTACGTGAGGAGCTGGCAAAATACATC
TCCAACAAGCCTTGCAGCAGCTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGCT
GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA
TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG
CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGTATTCGTCTAGCCAGTCAGATTGGTGCGGGTTTAGTCGGTGT
GATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGCTGCAAACCCTCACCCACTTAC
GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC
CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC
AGGTCAATATCTCAGTGGCGTGAAAAAAATCGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC
TTAAAGGCGCAGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT
TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACAGCACTCAATGGCGCGACGACGGC
GACACCTGCGCCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC
GCACTCCTCGCTCCAACCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTATTTGCAGGAACACAAGAGTCT
CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTTAACGTCCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT
GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAACGCTATAACCGAGAAA
CACTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC
CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGATTGTCCTACATTCGTCTTGGGCAATCAGCCAC
CACCTTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCGCGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA
TTTTGGATGAACCAACCACGGGCCTACACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT
GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGACTGGATCATCGATTTAGGCCCCGAAGG
CGGCCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT
TCCTCAAGCCTTTGTTGAATTAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-236)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-398)

• ABC transporter (ABC_tran) (622-859)

3D structure

• AlphaFold DB: Q9KUW5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.9	100	0.581
uvrA	Streptococcus pneumoniae TIGR4	57.9	100	0.581
uvrA	Streptococcus pneumoniae D39	57.9	100	0.581