Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   DV131_RS01395 Genome accession   NZ_CP031246
Coordinates   243811..244431 (-) Length   206 a.a.
NCBI ID   WP_000839910.1    Uniprot ID   A0A0B7LL05
Organism   Streptococcus pneumoniae strain M26368     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 238811..249431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS01370 recA 239188..240354 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  DV131_RS01375 cinA 240409..241665 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  DV131_RS01380 - 241750..242766 (-) 1017 WP_000239278.1 LCP family protein -
  DV131_RS01385 - 242774..243292 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  DV131_RS01390 tsaE 243282..243725 (-) 444 WP_114865819.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  DV131_RS01395 comM 243811..244431 (-) 621 WP_000839910.1 hypothetical protein Regulator
  DV131_RS01405 - 244814..245677 (-) 864 WP_044814842.1 helix-turn-helix transcriptional regulator -
  DV131_RS11440 - 245866..246036 (+) 171 WP_114865820.1 PhrA family quorum-sensing system peptide -
  DV131_RS01415 - 246181..248196 (+) 2016 WP_114865821.1 DUF1430 domain-containing protein -
  DV131_RS01420 - 248198..248830 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23526.64 Da        Isoelectric Point: 10.1254

>NTDB_id=304676 DV131_RS01395 WP_000839910.1 243811..244431(-) (comM) [Streptococcus pneumoniae strain M26368]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTSLATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=304676 DV131_RS01395 WP_000839910.1 243811..244431(-) (comM) [Streptococcus pneumoniae strain M26368]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTAGTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LL05

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment