Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EWS90_RS19755 Genome accession   NZ_CP035739
Coordinates   4051840..4052463 (+) Length   207 a.a.
NCBI ID   WP_003111192.1    Uniprot ID   A0A0H2ZJZ4
Organism   Pseudomonas aeruginosa strain 1334/14     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4046840..4057463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EWS90_RS19730 (EWS90_19730) - 4047925..4048152 (-) 228 WP_003097347.1 DUF1161 domain-containing protein -
  EWS90_RS19735 (EWS90_19735) - 4048336..4048551 (-) 216 WP_003097345.1 dodecin -
  EWS90_RS19740 (EWS90_19740) trpI 4048652..4049539 (-) 888 WP_003111191.1 trpBA operon transcriptional activator TrpI -
  EWS90_RS19745 (EWS90_19745) trpB 4049643..4050851 (+) 1209 WP_003097340.1 tryptophan synthase subunit beta -
  EWS90_RS19750 (EWS90_19750) trpA 4050848..4051654 (+) 807 WP_003120671.1 tryptophan synthase subunit alpha -
  EWS90_RS19755 (EWS90_19755) letA 4051840..4052463 (+) 624 WP_003111192.1 response regulator transcription factor Regulator
  EWS90_RS19760 (EWS90_19760) - 4052471..4052836 (+) 366 WP_003097330.1 Hpt domain-containing protein -
  EWS90_RS19765 (EWS90_19765) - 4052815..4053192 (-) 378 WP_003114635.1 DOPA 4,5-dioxygenase family protein -
  EWS90_RS19770 (EWS90_19770) - 4053203..4054102 (-) 900 WP_010792427.1 choline sulfate utilization transcriptional regulator -
  EWS90_RS19775 (EWS90_19775) betC 4054230..4055741 (+) 1512 WP_096861992.1 choline-sulfatase -
  EWS90_RS19780 (EWS90_19780) - 4055758..4056681 (+) 924 WP_003115797.1 choline ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 22859.66 Da        Isoelectric Point: 10.1491

>NTDB_id=304500 EWS90_RS19755 WP_003111192.1 4051840..4052463(+) (letA) [Pseudomonas aeruginosa strain 1334/14]
MSKVLIVDDHPAIRLAVRLLFERDGFTIVGEADNGAEALQVARKKSPDLAILDIGIPKIDGLEVIARLKSLKLDTKVLVL
TRQNPAQFAPRCLQAGAMGFVSKRENLSELLLAAKAVLAGYIHFPTGALRSINQQSRDNEARMLESLSDREMTVLQYLAN
GNTNKAIAQQLFLSEKTVSTYKSRIMLKLNAHSLAGLIDFARRHELI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=304500 EWS90_RS19755 WP_003111192.1 4051840..4052463(+) (letA) [Pseudomonas aeruginosa strain 1334/14]
ATGAGTAAGGTGCTGATCGTCGATGATCATCCCGCTATCCGCCTGGCCGTGCGCTTGCTGTTCGAGCGCGACGGTTTCAC
CATCGTCGGCGAGGCCGACAACGGTGCCGAAGCCCTGCAGGTAGCCCGCAAGAAGTCTCCCGACCTGGCCATCCTGGACA
TCGGCATCCCCAAGATCGACGGTCTCGAAGTGATAGCCCGCCTGAAGTCCCTGAAGCTGGACACCAAGGTCCTGGTCCTG
ACCCGGCAGAATCCGGCGCAGTTCGCCCCGCGCTGCCTGCAGGCCGGCGCCATGGGCTTCGTCAGCAAAAGGGAAAACCT
CTCCGAGCTGCTGCTCGCCGCCAAGGCCGTGCTGGCCGGCTACATCCACTTCCCCACCGGGGCGTTGCGCAGCATCAACC
AGCAGAGCCGCGACAACGAGGCCCGCATGCTGGAAAGCCTTTCCGACCGCGAGATGACCGTGCTGCAGTACCTGGCCAAC
GGCAACACCAACAAGGCCATCGCCCAGCAGCTGTTCCTCAGCGAGAAAACCGTGAGCACCTACAAGTCACGCATCATGCT
GAAACTCAACGCCCATTCCCTGGCCGGCCTGATCGATTTCGCCCGCCGCCACGAGCTGATCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Bacterial regulatory proteins, luxR family (GerE)

(145-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZJZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

35.377

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.377

100

0.362

Multiple sequence alignment