Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV369_RS09070 Genome accession   NZ_CP031239
Coordinates   1841793..1842485 (+) Length   230 a.a.
NCBI ID   WP_050948983.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M13034     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1836793..1847485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV369_RS09050 ampD 1838070..1838624 (-) 555 WP_005691822.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV369_RS09055 pilA 1838739..1839188 (+) 450 WP_005691824.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV369_RS09060 pilB 1839185..1840579 (+) 1395 WP_005691826.1 GspE/PulE family protein Machinery gene
  DV369_RS09065 pilC 1840576..1841796 (+) 1221 WP_050948984.1 type II secretion system F family protein Machinery gene
  DV369_RS09070 pilD 1841793..1842485 (+) 693 WP_050948983.1 A24 family peptidase Machinery gene
  DV369_RS09075 rho 1842539..1843801 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  DV369_RS09080 metJ 1844049..1844366 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV369_RS09085 cueR 1844380..1844766 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DV369_RS09090 - 1844843..1845049 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  DV369_RS09095 - 1845135..1845341 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV369_RS09100 - 1845415..1845621 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV369_RS09105 - 1845707..1845913 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26732.74 Da        Isoelectric Point: 8.5499

>NTDB_id=304449 DV369_RS09070 WP_050948983.1 1841793..1842485(+) (pilD) [Haemophilus influenzae strain M13034]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNRSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYC
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAIIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=304449 DV369_RS09070 WP_050948983.1 1841793..1842485(+) (pilD) [Haemophilus influenzae strain M13034]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTATCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCAGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACTGC
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCGGCTATCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

98.696

100

0.987
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment