Detailed information NTG0304429

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EPB55_RS12115
• Genome accession: NZ_CP035731
• Coordinates: 2441543..2444116 (+)
• Length: 857 a.a.
• NCBI ID: WP_045596288.1
• Uniprot ID: -
• Organism: Vibrio vulnificus strain 2142-77
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2436543..2449116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EPB55_RS12090	raiA	2436749..2437072 (-)	324	WP_011078575.1	ribosome-associated translation inhibitor RaiA	-
EPB55_RS12095	-	2437406..2438743 (-)	1338	WP_103277047.1	IS4-like element ISVvu3 family transposase	-
EPB55_RS12100	comL	2438867..2439592 (-)	726	WP_011078574.1	outer membrane protein assembly factor BamD	Machinery gene
EPB55_RS12105	rluD	2439729..2440705 (+)	977	Protein_2267	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EPB55_RS12110	pgeF	2440709..2441425 (+)	717	WP_193783991.1	peptidoglycan editing factor PgeF	-
EPB55_RS12115	clpC	2441543..2444116 (+)	2574	WP_045596288.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 96066.97 Da
• Isoelectric Point: 5.2933

>NTDB_id=304429 EPB55_RS12115 WP_045596288.1 2441543..2444116(+) (clpC) [Vibrio vulnificus strain 2142-77]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTILNVDVTHLRSKLSEMLDRLPKVSGIGGD
VQLSSAMGAMFNLCDKIAQKRQDAYISSEIFLLAAIEDRGPLGQLFKELGLTEQKVSQAIEQIRGGQKVNDQNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELSKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYVSDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLRSLNEELNEKEREFAELEEIWNAEKAALSGTQHIKAALE
QARMDMEFARRAGDLSRMSELQYGRIPELEKQLDLATQAEMQEMTLLKNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEEVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNKPIGSFLFLGPTGVGKTELCKTLANFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFAMLDYQGIKEQVMEVVTKHFRPEFLNRVDETVVFHPLGQDHIKSIAAIQLNRLANRMEEHGYQLEVSDKAL
ELIAQVGFDPVYGARPLKRAIQQSIENPLAKSILAGSVLPDKKIQLIVNNDQIVAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=304429 EPB55_RS12115 WP_045596288.1 2441543..2444116(+) (clpC) [Vibrio vulnificus strain 2142-77]
ATGCGTCTTGATCGATTTACCAGCAAATTTCAAATCGCTATCTCTGATGCACAATCATTGGCGTTAGGGCGCGATCATCA
GTACATTGAACCTGTTCACTTAATGGTGGCGCTGCTTGATCAAAATGGCAGTCCTATTCGTCCACTGTTGACCATCTTAA
ATGTGGATGTCACTCACCTACGTTCAAAACTCAGCGAAATGCTGGATCGCTTACCCAAAGTGAGCGGTATTGGTGGTGAT
GTACAGCTCTCCTCGGCCATGGGCGCGATGTTTAACTTGTGCGATAAGATTGCGCAAAAACGCCAAGATGCTTACATCTC
ATCTGAAATCTTTTTGCTCGCAGCAATCGAAGATAGAGGACCACTTGGTCAACTCTTCAAAGAACTTGGCTTGACCGAAC
AAAAAGTGAGTCAAGCTATCGAGCAAATTCGCGGCGGTCAAAAAGTGAACGATCAAAATGCGGAAGAGCTTCGCCAAGCG
TTAGAGAAATTTACCATTGATCTGACGGAACGCGCAGAGCAGGGCAAACTTGACCCTGTGATTGGTCGTGACGATGAAAT
TCGTCGCACCATTCAAGTATTGCAGCGTCGTACCAAAAACAACCCCGTGATCATCGGTGAACCCGGTGTCGGTAAAACCG
CCATCGTTGAAGGCTTAGCGCAACGCATCATCAATAACGAGGTACCTGAAGGTCTGCGTGGTCGCCGAGTGTTGTCACTC
GATATGGGCGCGTTGGTGGCTGGAGCGAAGTACCGTGGTGAGTTTGAAGAGCGACTTAAATCGGTATTAAATGAGTTGTC
TAAAGAAGAAGGTAATATCATCCTCTTTATTGATGAGCTTCATACCATGGTTGGCGCCGGTAAAGGTGAAGGTTCGATGG
ATGCGGGCAATATGCTCAAACCCGCATTGGCACGTGGTGAGTTACATTGTGTGGGGGCGACGACACTCGATGAGTATCGT
CAGTATATCGAGAAAGATCCTGCACTTGAGCGCCGCTTCCAAAAAGTGCTGGTTGATGAACCAACAGTGGAAGACACCAT
TGCAATTTTGCGCGGTTTAAAAGAACGCTATGAGCTGCATCATCATGTTGAAATTACCGATCCAGCGATCGTTGCTGCTG
CCAGTTTGTCGCATCGCTATGTTTCTGATCGTCAATTACCGGACAAAGCGATCGACCTCATCGACGAAGCCGCATCCAGT
ATTCGCATGCAGATCGATTCTAAACCCGAAGCTCTGGATAAGTTGGAGCGCAAAATCATCCAACTTAAGATAGAGCAACA
GGCGCTGAGTAATGAACACGATGAAGCGAGTGAAAAACGTCTGCGCTCACTTAACGAAGAGTTGAATGAGAAAGAGCGTG
AGTTTGCTGAGTTAGAGGAAATTTGGAACGCGGAAAAAGCCGCGCTGTCTGGTACTCAGCATATTAAAGCGGCGTTAGAG
CAAGCACGCATGGATATGGAGTTTGCAAGACGAGCGGGGGATCTTAGCCGCATGTCTGAGCTTCAATATGGCCGTATTCC
AGAGCTTGAGAAGCAACTTGACCTAGCAACGCAAGCAGAAATGCAGGAAATGACCTTGTTGAAAAACAAAGTCACCGATA
ATGAAATTGCGGAAGTGCTTTCTAAGCAAACGGGTATCCCTGTCTCCAAAATGCTTGAAGCAGAAAAAGAAAAATTACTT
CGCATGGAAGAGGTGCTGCATAAACGTGTTATTGGGCAGAAAGAGGCGGTGGAAGTTGTTGCGAATGCGATACGTCGCAG
CCGGGCGGGCTTGTCCGATCCCAATAAACCGATTGGTTCGTTCTTATTCTTAGGTCCAACCGGTGTGGGGAAAACGGAAC
TGTGCAAAACGTTGGCGAATTTCATGTTCGACAGTGAAGATGCCATGGTGCGTATCGACATGTCTGAGTTTATGGAGAAA
CACTCAGTGGCACGCTTAGTCGGTGCACCTCCGGGCTATGTGGGTTATGAAGAAGGTGGATATTTAACGGAAGCGGTTCG
ACGTAAGCCTTATTCAGTGATTTTGCTCGATGAAGTGGAAAAGGCACACCCTGATGTGTTCAACATCCTGCTACAAGTCT
TGGATGATGGTCGATTGACGGATGGACAAGGTAGAACGGTGGATTTCCGCAATACCGTGGTCATCATGACATCAAACCTA
GGCTCCAGCCGCATCCAAGAAAACTTCGCTATGTTGGATTACCAAGGCATCAAAGAACAGGTGATGGAAGTGGTGACCAA
GCACTTTAGACCGGAGTTTTTGAACCGTGTTGATGAGACAGTGGTCTTCCACCCACTTGGTCAAGACCATATTAAGTCGA
TCGCAGCGATTCAACTTAACCGCTTGGCGAATCGCATGGAAGAGCATGGCTATCAGTTGGAAGTGTCCGATAAAGCGCTT
GAATTGATCGCACAAGTTGGTTTTGACCCGGTTTACGGAGCAAGACCATTGAAACGAGCGATTCAGCAAAGTATCGAGAA
CCCACTGGCGAAATCTATTTTGGCGGGCTCGGTGCTACCGGATAAGAAAATACAGCTTATCGTCAACAACGACCAAATTG
TGGCACACCAATAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• AAA lid domain (AAA_lid_9) (342-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.828	100	0.474
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.54	100	0.415
clpE	Streptococcus mutans UA159	48.159	79.23	0.382
clpE	Streptococcus pneumoniae D39	48.154	78.996	0.38
clpE	Streptococcus pneumoniae Rx1	48.154	78.996	0.38
clpE	Streptococcus pneumoniae R6	48.154	78.996	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.009	80.397	0.37