Detailed information NTG0304002

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DV527_RS04685
• Genome accession: NZ_CP031196
• Coordinates: 975536..976579 (+)
• Length: 347 a.a.
• NCBI ID: WP_011302781.1
• Uniprot ID: -
• Organism: Staphylococcus saprophyticus strain 1A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 970536..981579

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV527_RS04660 (DV527_04670)	-	971560..972279 (+)	720	WP_002482838.1	type 1 glutamine amidotransferase	-
DV527_RS04665 (DV527_04675)	-	972418..973404 (-)	987	WP_002482841.1	aromatic acid exporter family protein	-
DV527_RS04670 (DV527_04680)	map	973579..974331 (+)	753	WP_011302778.1	type I methionyl aminopeptidase	-
DV527_RS04675 (DV527_04685)	-	974435..974821 (+)	387	WP_041079966.1	hypothetical protein	-
DV527_RS04680 (DV527_04690)	liaF	974838..975539 (+)	702	WP_011302780.1	cell wall-active antibiotics response protein LiaF	-
DV527_RS04685 (DV527_04695)	vraS	975536..976579 (+)	1044	WP_011302781.1	sensor histidine kinase	Regulator
DV527_RS04690 (DV527_04700)	vraR	976569..977198 (+)	630	WP_002482846.1	response regulator transcription factor	Regulator
DV527_RS04695 (DV527_04705)	-	977355..978527 (-)	1173	WP_002482847.1	YihY/virulence factor BrkB family protein	-
DV527_RS04700 (DV527_04710)	-	978939..979223 (-)	285	WP_002482848.1	hypothetical protein	-
DV527_RS04705 (DV527_04715)	-	979230..979694 (-)	465	WP_037538133.1	low molecular weight protein-tyrosine-phosphatase	-
DV527_RS04710 (DV527_04720)	-	979829..980032 (+)	204	WP_002482850.1	DUF1128 family protein	-
DV527_RS04715 (DV527_04725)	-	980046..981284 (+)	1239	WP_041079969.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40050.55 Da
• Isoelectric Point: 6.4221

>NTDB_id=304002 DV527_RS04685 WP_011302781.1 975536..976579(+) (vraS) [Staphylococcus saprophyticus strain 1A]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=304002 DV527_RS04685 WP_011302781.1 975536..976579(+) (vraS) [Staphylococcus saprophyticus strain 1A]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCGTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGTCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTGAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873