Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DU470_RS13975 Genome accession   NZ_CP031131
Coordinates   2685536..2686201 (-) Length   221 a.a.
NCBI ID   WP_000697879.1    Uniprot ID   -
Organism   Staphylococcus aureus strain E16SA093     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2680536..2691201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DU470_RS13955 (DU470_13955) - 2681005..2681118 (-) 114 Protein_2599 hypothetical protein -
  DU470_RS13960 (DU470_13960) - 2681777..2683777 (-) 2001 WP_000776739.1 ABC transporter permease -
  DU470_RS13965 (DU470_13965) - 2683774..2684529 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  DU470_RS13970 (DU470_13970) braS 2684638..2685525 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  DU470_RS13975 (DU470_13975) braR 2685536..2686201 (-) 666 WP_000697879.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  DU470_RS13980 (DU470_13980) - 2686227..2686427 (-) 201 WP_000604727.1 hypothetical protein -
  DU470_RS13985 (DU470_13985) - 2686625..2688049 (+) 1425 WP_000953762.1 alkaline phosphatase -
  DU470_RS14455 - 2688119..2688229 (+) 111 WP_001791296.1 hypothetical protein -
  DU470_RS13995 (DU470_13995) - 2688332..2688787 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  DU470_RS14000 (DU470_14000) - 2689032..2689793 (-) 762 WP_000323447.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25388.46 Da        Isoelectric Point: 4.7961

>NTDB_id=303646 DU470_RS13975 WP_000697879.1 2685536..2686201(-) (braR) [Staphylococcus aureus strain E16SA093]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=303646 DU470_RS13975 WP_000697879.1 2685536..2686201(-) (braR) [Staphylococcus aureus strain E16SA093]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment