Detailed information NTG0303645

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DU470_RS13970
• Genome accession: NZ_CP031131
• Coordinates: 2684638..2685525 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain E16SA093
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2679638..2690525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DU470_RS13935 (DU470_13935)	-	2679656..2679748 (+)	93	WP_010956583.1	hypothetical protein	-
DU470_RS13940 (DU470_13940)	-	2679856..2680353 (-)	498	WP_001065269.1	glutathione peroxidase	-
DU470_RS13945 (DU470_13945)	-	2680363..2680623 (-)	261	WP_001789910.1	hypothetical protein	-
DU470_RS13955 (DU470_13955)	-	2681005..2681118 (-)	114	Protein_2599	hypothetical protein	-
DU470_RS13960 (DU470_13960)	-	2681777..2683777 (-)	2001	WP_000776739.1	ABC transporter permease	-
DU470_RS13965 (DU470_13965)	-	2683774..2684529 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DU470_RS13970 (DU470_13970)	braS	2684638..2685525 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DU470_RS13975 (DU470_13975)	braR	2685536..2686201 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DU470_RS13980 (DU470_13980)	-	2686227..2686427 (-)	201	WP_000604727.1	hypothetical protein	-
DU470_RS13985 (DU470_13985)	-	2686625..2688049 (+)	1425	WP_000953762.1	alkaline phosphatase	-
DU470_RS14455	-	2688119..2688229 (+)	111	WP_001791296.1	hypothetical protein	-
DU470_RS13995 (DU470_13995)	-	2688332..2688787 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DU470_RS14000 (DU470_14000)	-	2689032..2689793 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=303645 DU470_RS13970 WP_000143420.1 2684638..2685525(-) (braS) [Staphylococcus aureus strain E16SA093]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=303645 DU470_RS13970 WP_000143420.1 2684638..2685525(-) (braS) [Staphylococcus aureus strain E16SA093]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993