Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ETT47_RS04075 Genome accession   NZ_CP035452
Coordinates   792063..793859 (+) Length   598 a.a.
NCBI ID   WP_053308333.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm123     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 787063..798859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT47_RS04060 (ETT47_04050) - 788621..789409 (+) 789 WP_002984836.1 response regulator transcription factor -
  ETT47_RS04065 (ETT47_04055) - 789403..790449 (+) 1047 WP_011017728.1 extracellular solute-binding protein -
  ETT47_RS04070 (ETT47_04060) - 790564..791961 (+) 1398 WP_136099052.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  ETT47_RS04075 (ETT47_04065) uvrC 792063..793859 (+) 1797 WP_053308333.1 excinuclease ABC subunit UvrC Machinery gene
  ETT47_RS04080 (ETT47_04070) - 794043..794645 (+) 603 WP_002989923.1 nitroreductase family protein -
  ETT47_RS04085 (ETT47_04075) pepV 794770..796179 (+) 1410 WP_032465003.1 dipeptidase PepV -
  ETT47_RS04090 (ETT47_04080) mnmE 796247..797623 (-) 1377 WP_136099053.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  ETT47_RS04095 (ETT47_04085) rplJ 797959..798459 (+) 501 WP_002984821.1 50S ribosomal protein L10 -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68929.75 Da        Isoelectric Point: 9.6460

>NTDB_id=303265 ETT47_RS04075 WP_053308333.1 792063..793859(+) (uvrC) [Streptococcus pyogenes strain emm123]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEIN
LIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDYISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=303265 ETT47_RS04075 WP_053308333.1 792063..793859(+) (uvrC) [Streptococcus pyogenes strain emm123]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCCAAGAATTTGAAAAAACGCGTCCGGTCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AGTTACTAGTATCTGAGATTGTAGATTTCGAATATATTGTAACAGAGTCAGATACCGAAGCGCTTTTGTTGGAAATTAAC
TTGATTCAAAAAAATATGCCTAAGTACAACATCAAGTTAAAAGATGATAAATCTTATCCCTTTCTCAAAATCACAAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGACTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATGT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGATCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GATTTGCAAGATAGAGATATCTTTGGCTATTATGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCCAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTACTAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCAGTTACTTA
AGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGTCCAGTTGCGGCTATGGTTGTT
TTTGTTGATGGCAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAGTCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAGCACCAGACCCATGATTTGCTTTTTGGAAACCCGCTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTACGACGTAAAAATT
CTTTTTCATCAACATTAGATTATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

73.684

98.495

0.726
  uvrC Streptococcus pneumoniae R6

73.684

98.495

0.726
  uvrC Streptococcus pneumoniae D39

73.684

98.495

0.726