Detailed information NTG0303262

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT47_RS03620
• Genome accession: NZ_CP035452
• Coordinates: 698879..700978 (-)
• Length: 699 a.a.
• NCBI ID: WP_109991863.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm123
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 693879..705978

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT47_RS03590 (ETT47_03580)	-	694356..695195 (+)	840	WP_011017679.1	thymidylate synthase	-
ETT47_RS03595 (ETT47_03585)	-	695275..695772 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT47_RS03600 (ETT47_03590)	-	695792..695962 (+)	171	WP_002990165.1	hypothetical protein	-
ETT47_RS03605 (ETT47_03595)	clpX	696092..697321 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT47_RS03610 (ETT47_03600)	yihA	697331..697930 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT47_RS03615 (ETT47_03605)	-	698078..698821 (+)	744	WP_002984942.1	hypothetical protein	-
ETT47_RS03620 (ETT47_03610)	clpC	698879..700978 (-)	2100	WP_109991863.1	AAA family ATPase	Regulator
ETT47_RS03625 (ETT47_03615)	rpiA	701356..702039 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-
ETT47_RS03630 (ETT47_03620)	-	702116..703327 (+)	1212	WP_109991862.1	phosphopentomutase	-
ETT47_RS03635 (ETT47_03625)	arsC	703343..703783 (+)	441	WP_109991861.1	arsenate reductase (glutaredoxin)	-
ETT47_RS03640 (ETT47_03630)	-	703767..704576 (+)	810	WP_136099035.1	purine-nucleoside phosphorylase	-
ETT47_RS03645 (ETT47_03635)	deoD	705094..705807 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77406.46 Da
• Isoelectric Point: 5.5561

>NTDB_id=303262 ETT47_RS03620 WP_109991863.1 698879..700978(-) (clpC) [Streptococcus pyogenes strain emm123]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMCIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFSQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=303262 ETT47_RS03620 WP_109991863.1 698879..700978(-) (clpC) [Streptococcus pyogenes strain emm123]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAATCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCACCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGTGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTCACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTCATTATTGCTACATCAAATGCCGGTTTTAGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (259-353)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.799	100	0.471
clpE	Streptococcus mutans UA159	48.913	92.132	0.451
clpE	Streptococcus pneumoniae TIGR4	49.117	89.127	0.438
clpE	Streptococcus pneumoniae Rx1	49.117	89.127	0.438
clpE	Streptococcus pneumoniae D39	49.117	89.127	0.438
clpE	Streptococcus pneumoniae R6	49.117	89.127	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	44.361	95.136	0.422
clpC	Streptococcus pneumoniae Rx1	41.564	93.276	0.388
clpC	Streptococcus pneumoniae D39	41.564	93.276	0.388
clpC	Streptococcus thermophilus LMD-9	42.476	91.273	0.388
clpC	Streptococcus thermophilus LMG 18311	42.32	91.273	0.386
clpC	Streptococcus pneumoniae TIGR4	42.54	90.129	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.041	93.419	0.383
clpC	Streptococcus mutans UA159	41.498	91.702	0.381