Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   ETT49_RS08135 Genome accession   NZ_CP035450
Coordinates   1630448..1631215 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm93.4     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1625448..1636215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT49_RS08120 (ETT49_08115) hexB 1625957..1627939 (-) 1983 WP_136110754.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT49_RS08125 (ETT49_08120) - 1628034..1629185 (-) 1152 WP_014635780.1 site-specific integrase -
  ETT49_RS08130 (ETT49_08125) - 1629434..1629577 (+) 144 WP_011185066.1 putative holin-like toxin -
  ETT49_RS08135 (ETT49_08130) irvR 1630448..1631215 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  ETT49_RS08140 (ETT49_08135) - 1631369..1631575 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  ETT49_RS08145 (ETT49_08140) - 1631609..1632376 (+) 768 WP_080277853.1 Bro-N domain-containing protein -
  ETT49_RS08150 (ETT49_08145) - 1632386..1632997 (+) 612 WP_136098507.1 Bro-N domain-containing protein -
  ETT49_RS08155 (ETT49_08150) - 1633018..1633425 (+) 408 WP_002992501.1 hypothetical protein -
  ETT49_RS08715 - 1633438..1633560 (+) 123 WP_011285272.1 hypothetical protein -
  ETT49_RS08160 (ETT49_08155) - 1633843..1634364 (+) 522 WP_002992498.1 Rha family transcriptional regulator -
  ETT49_RS08170 (ETT49_08165) - 1634971..1635375 (+) 405 WP_227868741.1 hypothetical protein -
  ETT49_RS08175 (ETT49_08170) - 1635477..1635818 (+) 342 WP_010922762.1 hypothetical protein -
  ETT49_RS08180 (ETT49_08175) - 1635805..1636026 (+) 222 WP_010922763.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=303119 ETT49_RS08135 WP_003058809.1 1630448..1631215(-) (irvR) [Streptococcus pyogenes strain emm93.4]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=303119 ETT49_RS08135 WP_003058809.1 1630448..1631215(-) (irvR) [Streptococcus pyogenes strain emm93.4]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4

Multiple sequence alignment