Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ETT50_RS05000 Genome accession   NZ_CP035449
Coordinates   966688..968484 (-) Length   598 a.a.
NCBI ID   WP_032465002.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm56     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 961688..973484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT50_RS04980 (ETT50_04980) rplJ 962087..962587 (-) 501 WP_002984821.1 50S ribosomal protein L10 -
  ETT50_RS04985 (ETT50_04985) mnmE 962922..964298 (+) 1377 WP_002989919.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  ETT50_RS04990 (ETT50_04990) pepV 964366..965775 (-) 1410 WP_032465003.1 dipeptidase PepV -
  ETT50_RS04995 (ETT50_04995) - 965900..966502 (-) 603 WP_002989923.1 nitroreductase family protein -
  ETT50_RS05000 (ETT50_05000) uvrC 966688..968484 (-) 1797 WP_032465002.1 excinuclease ABC subunit UvrC Machinery gene
  ETT50_RS05005 (ETT50_05005) - 968586..969983 (-) 1398 WP_014407552.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  ETT50_RS05010 (ETT50_05010) - 970098..971144 (-) 1047 WP_032465001.1 extracellular solute-binding protein -
  ETT50_RS05015 (ETT50_05015) - 971138..971926 (-) 789 WP_002984836.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68829.68 Da        Isoelectric Point: 9.7186

>NTDB_id=302994 ETT50_RS05000 WP_032465002.1 966688..968484(-) (uvrC) [Streptococcus pyogenes strain emm56]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEIN
LIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEGLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=302994 ETT50_RS05000 WP_032465002.1 966688..968484(-) (uvrC) [Streptococcus pyogenes strain emm56]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCCAAGAATTTGAAAAAACGCGTCCGGTCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AGTTATTAGTATCTGAGATTGTAGATTTCGAATATATTGTAACAGAGTCAGATACCGAAGCGCTTTTGTTGGAAATTAAC
TTGATTCAAAAAAATATGCCTAAGTACAACATCAAGTTAAAAGATGATAAATCTTATCCCTTTCTCAAAATCACAAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGATTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATGT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGGTCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCTGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GACTTACAAGACAGGGATATTTTTGGCTACTTTGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCTAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTACTAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCAGTTACTTA
AGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAGTCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAGCACCAGACCCATGATTTGCTTTTTGGAAACCCGCTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTGCGACGTAAAAATT
CTTTTTCATCAACATTAGATCATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

73.345

98.495

0.722
  uvrC Streptococcus pneumoniae TIGR4

73.345

98.495

0.722
  uvrC Streptococcus pneumoniae D39

73.345

98.495

0.722