Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ETT51_RS04800 Genome accession   NZ_CP035448
Coordinates   906376..908172 (+) Length   598 a.a.
NCBI ID   WP_063632475.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 901376..913172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS04785 (ETT51_04830) - 902934..903722 (+) 789 WP_020905146.1 response regulator transcription factor -
  ETT51_RS04790 (ETT51_04835) - 903716..904762 (+) 1047 WP_002984833.1 extracellular solute-binding protein -
  ETT51_RS04795 (ETT51_04840) - 904877..906274 (+) 1398 WP_063632474.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  ETT51_RS04800 (ETT51_04845) uvrC 906376..908172 (+) 1797 WP_063632475.1 excinuclease ABC subunit UvrC Machinery gene
  ETT51_RS04805 (ETT51_04850) - 908358..908960 (+) 603 WP_002989923.1 nitroreductase family protein -
  ETT51_RS04810 (ETT51_04855) pepV 909085..910494 (+) 1410 WP_023079436.1 dipeptidase PepV -
  ETT51_RS04815 (ETT51_04860) mnmE 910562..911938 (-) 1377 WP_063632477.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  ETT51_RS04820 (ETT51_04865) rplJ 912274..912774 (+) 501 WP_002984821.1 50S ribosomal protein L10 -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68945.76 Da        Isoelectric Point: 9.6619

>NTDB_id=302883 ETT51_RS04800 WP_063632475.1 906376..908172(+) (uvrC) [Streptococcus pyogenes strain emm70]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEIN
LIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQINVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=302883 ETT51_RS04800 WP_063632475.1 906376..908172(+) (uvrC) [Streptococcus pyogenes strain emm70]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCCAAGAATTTGAAAAAACGCGTCCGATCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AGTTATTAGTATCTGAGATTGTAGATTTCGAATATATTGTAACAGAGTCAGATACCGAAGCGCTTTTGTTGGAAATTAAC
TTGATTCAAAAAAATATGCCTAAGTACAACATCAAGTTAAAAGATGATAAATCTTATCCCTTTCTCAAAATCACAAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGATTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATGT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGATCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GATTTGCAAGATAGAGATATCTTTGGCTATTATGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCCAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTACTAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCAGTTACTTA
GGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGTCCAGTTGCGGCTATGGTTGTT
TTTGTTGATGGCAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAATCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAACACCAGACCCATGATTTGCTTTTTGGAAACCCGCTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTGCGACGTAAAAATT
CTTTTTCATCAACATTAGATCATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

73.514

98.495

0.724
  uvrC Streptococcus pneumoniae D39

73.514

98.495

0.724
  uvrC Streptococcus pneumoniae TIGR4

73.514

98.495

0.724