Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT52_RS07335 Genome accession   NZ_CP035447
Coordinates   1419366..1420148 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain emm97.1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1414366..1425148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT52_RS07305 (ETT52_07295) gatB 1414447..1415886 (-) 1440 WP_136096689.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  ETT52_RS07310 (ETT52_07300) gatA 1415886..1417352 (-) 1467 WP_136109067.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT52_RS07315 (ETT52_07305) gatC 1417352..1417654 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT52_RS07320 (ETT52_07310) - 1417886..1418188 (-) 303 Protein_1356 putative PEP-binding protein -
  ETT52_RS07330 (ETT52_07320) - 1418665..1419219 (-) 555 WP_002992568.1 cysteine hydrolase family protein -
  ETT52_RS07335 (ETT52_07325) codY 1419366..1420148 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT52_RS07340 (ETT52_07330) - 1420366..1421580 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  ETT52_RS07345 (ETT52_07335) - 1421811..1422263 (+) 453 WP_002992571.1 universal stress protein -
  ETT52_RS07350 (ETT52_07340) - 1422386..1423774 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  ETT52_RS07355 (ETT52_07345) - 1423846..1424811 (+) 966 WP_023078713.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=302813 ETT52_RS07335 WP_002983278.1 1419366..1420148(-) (codY) [Streptococcus pyogenes strain emm97.1]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=302813 ETT52_RS07335 WP_002983278.1 1419366..1420148(-) (codY) [Streptococcus pyogenes strain emm97.1]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAATCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment