Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DS740_RS06135 Genome accession   NZ_CP030937
Coordinates   1187406..1188062 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus sp. DM2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1182406..1193062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DS740_RS06110 (DS740_06110) oppF 1182871..1183788 (+) 918 WP_069703689.1 oligopeptide ABC transporter ATP-binding protein OppF -
  DS740_RS06115 (DS740_06115) - 1183895..1185112 (+) 1218 WP_080477793.1 MFS transporter -
  DS740_RS06120 (DS740_06120) - 1185276..1185854 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  DS740_RS06125 (DS740_06125) spx 1186035..1186430 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  DS740_RS06130 (DS740_06130) - 1186473..1187129 (-) 657 WP_003232944.1 TerC family protein -
  DS740_RS22680 - 1187299..1187439 (+) 141 WP_119122854.1 hypothetical protein -
  DS740_RS06135 (DS740_06135) mecA 1187406..1188062 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  DS740_RS22685 - 1188057..1188179 (-) 123 WP_003232940.1 hypothetical protein -
  DS740_RS06140 (DS740_06140) coiA 1188223..1189374 (+) 1152 WP_069703690.1 competence protein CoiA Machinery gene
  DS740_RS06145 (DS740_06145) pepF 1189604..1191433 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  DS740_RS06150 (DS740_06150) - 1191471..1191638 (-) 168 WP_003244944.1 hypothetical protein -
  DS740_RS06160 (DS740_06160) spxH 1191952..1192851 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=302588 DS740_RS06135 WP_003232942.1 1187406..1188062(+) (mecA) [Bacillus sp. DM2]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=302588 DS740_RS06135 WP_003232942.1 1187406..1188062(+) (mecA) [Bacillus sp. DM2]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment