Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ETT56_RS09255 Genome accession   NZ_CP035443
Coordinates   1810214..1812196 (-) Length   660 a.a.
NCBI ID   WP_023610727.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm58     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1805214..1817196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT56_RS09230 (ETT56_09220) recA 1805250..1806386 (-) 1137 WP_023610714.1 recombinase RecA -
  ETT56_RS09235 (ETT56_09225) cinA 1806475..1807746 (-) 1272 WP_023610745.1 competence/damage-inducible protein A Machinery gene
  ETT56_RS09240 (ETT56_09230) - 1807815..1808375 (-) 561 WP_023610776.1 DNA-3-methyladenine glycosylase I -
  ETT56_RS09245 (ETT56_09235) ruvA 1808385..1808981 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT56_RS09250 (ETT56_09240) - 1808983..1810203 (-) 1221 WP_002991361.1 MFS transporter -
  ETT56_RS09255 (ETT56_09245) hexB 1810214..1812196 (-) 1983 WP_023610727.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT56_RS09260 (ETT56_09250) - 1812291..1813436 (-) 1146 WP_063632873.1 site-specific integrase -
  ETT56_RS09920 - 1813518..1814186 (-) 669 WP_012560499.1 helix-turn-helix domain-containing protein -
  ETT56_RS09270 (ETT56_09260) - 1814353..1814538 (+) 186 WP_012560498.1 DNA-binding transcriptional regulator -
  ETT56_RS09275 (ETT56_09265) - 1814554..1814802 (+) 249 WP_063632871.1 hypothetical protein -
  ETT56_RS09280 (ETT56_09270) - 1815330..1815539 (+) 210 WP_009880499.1 hypothetical protein -
  ETT56_RS09925 (ETT56_09275) - 1815536..1815727 (+) 192 WP_063632869.1 hypothetical protein -
  ETT56_RS09930 (ETT56_09280) - 1815749..1815943 (+) 195 WP_063632867.1 hypothetical protein -
  ETT56_RS09295 (ETT56_09285) - 1815955..1816284 (+) 330 WP_000174498.1 hypothetical protein -
  ETT56_RS09300 (ETT56_09290) - 1816287..1816559 (+) 273 WP_063631415.1 hypothetical protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74328.89 Da        Isoelectric Point: 5.8718

>NTDB_id=302458 ETT56_RS09255 WP_023610727.1 1810214..1812196(-) (hexB) [Streptococcus pyogenes strain emm58]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLAISNADLDFEVSGYVSLP
ELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAVDNSVKVEK
AELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLENEEKSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=302458 ETT56_RS09255 WP_023610727.1 1810214..1812196(-) (hexB) [Streptococcus pyogenes strain emm58]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCGTTGAAATTGAAGAGTCTGGCCTTAAGA
TGATACAGGTTACAGACAACGGTGAGGGAATGTCTCATGAAGATTTACCTTTAAGTCTGCGTCGCCACGCTACTAGTAAA
ATTAAGAGTCAGAGTGATTTGTTTAGAATTAGAACACTTGGCTTCCGTGGAGAGGCTTTACCGTCTGTTGCCTCTATCAG
TAAAATCACGATAAAAACAGCAACAAAAGAAGTCACTCACGGTTCTCTTCTTATAGCTACTGGTGGGGAAATTGAGACAC
TTGAAGCGATCTCAACTCCTACTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACGCCTGCTCGTCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAACCGGTTGAGTTTGGCACATCCAGAAGTTGCTTT
CACACTGATTAGTGATGGTCGCCAATTAACTCAGACATCAGGAACTGGCGATTTACGCCAAGCAATTGCAGGGATTTATG
GTTTGAATACTACCAAAAAAATGCTGGCTATCTCTAATGCTGATTTGGATTTTGAAGTTTCCGGCTATGTTAGCTTGCCA
GAGTTGACACGCGCCAACCGTAATTACATGACGATTTTGGTTAATGGGCGTTACATCAAGAATTTCTTGCTTAATCGAGC
AATTCTTGATGGTTACGGTTCTAAGCTCATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGATCCCTATT
TGGCCGATGTCAATGTTCATCCCACAAAACAAGAGGTTCGTATTTCAAAAGAGCGTGAATTAATGGCTTTAATTAGCACG
GCTATTTCAGAGAGTCTTAAGGAACAAGATTTGATTCCAGATGCTCTGGAAAACTTAGCCAAATCAAGCACACGACATTT
CTCTAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGGCTTTATTATGATCCTCAAAAGAATGACTTTTTTGTCA
AAGAGTCGGCTGTCTCGGAAAAAATACCTGAAACTGATTTTTATTCCGGCGCTGTTGACAACAGTGTAAAGGTTGAAAAA
GCAGAGCTGTTACCCCACTCAGAAGAAGTTATAGGACCTTCTTCGGTTAAACACGCAAGTCGTCCCCAGAATACCTTTAC
CGAGACTGATCATCCTAATCTTGACTTAAAAAACAGACAAAAGTTATCTCAAATGTTGAATCGCTTGGAAAATGAAGAAA
AATCAGTATTTCCTGAATTGGATTATTTTGGTCAGATGCATGGAACTTATCTCTTTGCTCAAGGTAAAGATGGCTTATTT
ATTATCGATCAGCATGCTGCTCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATTGGCGACGTTGACAGTAGTTT
ACAGCAGCTATTGGTACCCTATTTGTTTGAGTTTTCTGGTTCTGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTCGGTATCTTCTTAGAAGTTTATGGGCACAATACTTTCATTTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTGGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTATTGATTAATTTTAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGAATTCAAGAAAATCACACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

67.018

100

0.674