Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DTA40_RS01885 Genome accession   NZ_CP030928
Coordinates   343719..345038 (+) Length   439 a.a.
NCBI ID   WP_024704193.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS18     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 338719..350038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DTA40_RS01860 (DTA40_01880) - 339573..340337 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -
  DTA40_RS01865 (DTA40_01885) - 340337..341047 (+) 711 WP_011680767.1 ABC transporter ATP-binding protein -
  DTA40_RS01870 (DTA40_01890) - 341183..341843 (+) 661 Protein_320 CBS and ACT domain-containing protein -
  DTA40_RS01875 (DTA40_01895) cysK 342010..342936 (-) 927 WP_011680768.1 cysteine synthase A -
  DTA40_RS01880 (DTA40_01900) - 343038..343664 (-) 627 WP_011680769.1 YigZ family protein -
  DTA40_RS01885 (DTA40_01905) comFA/cflA 343719..345038 (+) 1320 WP_024704193.1 DEAD/DEAH box helicase Machinery gene
  DTA40_RS01890 (DTA40_01910) - 345019..345681 (+) 663 WP_011680771.1 ComF family protein -
  DTA40_RS01895 (DTA40_01915) raiA 345760..346308 (+) 549 WP_011680772.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50601.74 Da        Isoelectric Point: 9.7105

>NTDB_id=302411 DTA40_RS01885 WP_024704193.1 343719..345038(+) (comFA/cflA) [Streptococcus thermophilus strain CS18]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTSEKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSVT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELTILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=302411 DTA40_RS01885 WP_024704193.1 343719..345038(+) (comFA/cflA) [Streptococcus thermophilus strain CS18]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTGACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTCTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGAGAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTGTTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGACAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-206)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae Rx1

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae D39

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae R6

55.452

98.178

0.544
  comFA/cflA Streptococcus mitis NCTC 12261

55.116

97.95

0.54
  comFA/cflA Streptococcus mitis SK321

54.186

97.95

0.531
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.011

99.089

0.367

Multiple sequence alignment