Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   DR994_RS05970 Genome accession   NZ_CP030927
Coordinates   1156396..1157913 (-) Length   505 a.a.
NCBI ID   WP_173940561.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS9     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1151396..1162913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR994_RS05945 - 1151568..1152237 (-) 670 Protein_1138 HI_0552 family protein -
  DR994_RS05950 (DR994_06115) der 1152301..1153611 (-) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -
  DR994_RS05955 (DR994_06120) dnaI 1153717..1154619 (-) 903 WP_002946786.1 primosomal protein DnaI -
  DR994_RS05960 (DR994_06125) - 1154623..1155798 (-) 1176 WP_002949643.1 DnaD domain protein -
  DR994_RS05965 (DR994_06130) nrdR 1155795..1156274 (-) 480 WP_002949642.1 transcriptional regulator NrdR -
  DR994_RS05970 (DR994_06135) covS 1156396..1157913 (-) 1518 WP_173940561.1 HAMP domain-containing histidine kinase Regulator
  DR994_RS05975 (DR994_06140) covR 1157910..1158599 (-) 690 WP_002949638.1 response regulator transcription factor Regulator
  DR994_RS05980 (DR994_06145) - 1158755..1159291 (-) 537 WP_173940562.1 YceD family protein -
  DR994_RS05985 (DR994_06150) rsmG 1159588..1160301 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DR994_RS05990 (DR994_06155) - 1160371..1161735 (+) 1365 WP_275946675.1 potassium transporter TrkG -
  DR994_RS05995 (DR994_06160) - 1161775..1162446 (+) 672 WP_002946492.1 TrkA family potassium uptake protein -
  DR994_RS10020 (DR994_06165) - 1162463..1162633 (-) 171 Protein_1149 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57550.91 Da        Isoelectric Point: 5.1731

>NTDB_id=302361 DR994_RS05970 WP_173940561.1 1156396..1157913(-) (covS) [Streptococcus thermophilus strain CS9]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKAIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGDLALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=302361 DR994_RS05970 WP_173940561.1 1156396..1157913(-) (covS) [Streptococcus thermophilus strain CS9]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAGCTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGGCCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.622

99.406

0.941

Multiple sequence alignment