Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ETT60_RS04545 Genome accession   NZ_CP035439
Coordinates   859435..861231 (+) Length   598 a.a.
NCBI ID   WP_136114686.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm77     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 854435..866231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT60_RS04520 (ETT60_04510) - 854745..855791 (+) 1047 WP_129284045.1 extracellular solute-binding protein -
  ETT60_RS04525 (ETT60_04515) - 855888..856393 (+) 506 Protein_819 YkgJ family cysteine cluster protein -
  ETT60_RS04530 (ETT60_04520) - 856570..857136 (+) 567 WP_136095641.1 sugar O-acetyltransferase -
  ETT60_RS04535 (ETT60_04525) - 857152..857841 (+) 690 WP_161761972.1 YjjG family noncanonical pyrimidine nucleotidase -
  ETT60_RS04540 (ETT60_04530) - 857936..859333 (+) 1398 WP_111694791.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  ETT60_RS04545 (ETT60_04535) uvrC 859435..861231 (+) 1797 WP_136114686.1 excinuclease ABC subunit UvrC Machinery gene
  ETT60_RS04550 (ETT60_04540) - 861417..862019 (+) 603 WP_002989923.1 nitroreductase family protein -
  ETT60_RS04555 (ETT60_04545) pepV 862144..863553 (+) 1410 WP_129284041.1 dipeptidase PepV -
  ETT60_RS04560 (ETT60_04550) mnmE 863621..864997 (-) 1377 WP_129284040.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
  ETT60_RS04565 (ETT60_04555) rplJ 865333..865833 (+) 501 WP_002984821.1 50S ribosomal protein L10 -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68915.65 Da        Isoelectric Point: 9.6312

>NTDB_id=302030 ETT60_RS04545 WP_136114686.1 859435..861231(+) (uvrC) [Streptococcus pyogenes strain emm77]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYYVDRGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQ
KNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTI
TAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=302030 ETT60_RS04545 WP_136114686.1 859435..861231(+) (uvrC) [Streptococcus pyogenes strain emm77]
ATGAACGAACTGATTAAACATAAACTAGAACTCTTACCAGACAGCCCTGGCTGTTACTTACATAAAGATAAAGAAGGAAC
TATTATCTATGTCGGTAAGGCCAAGAATTTGAAAAAACGCGTCCGGTCCTATTTTCGTGGGAGCCATGATACCAAAACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTGACCGAATCAAATACTGAGGCTCTCTTGCTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAGTATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GTCTTTTCCTCGGTTAGTGATTACAAGATATATTAAGAAAAATGATGGATTGTACTTTGGGCCCTACCCAGACTCTTACA
CTGCTAATGAAGTTAAAAAGTTATTAGATAGGATTTTTCCATTTAAAAAGTGTAAAAATCCTATCAATAAGGTCTGTTTT
TATTACCATTTAGGCCAGTGCTGTGCTCATACCATTTGTCATACAGACAAGGCCTATTGGGATCGTTTAATTGATGATGT
TAAGCACTTTTTAAATGGTAAAGATGACAAAATTATTGAAGATCTTCGTTCTAAGATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGGGTGATGAGCAAG
GATTTGCAAGATAGAGATATCTTTGGCTATTATGTTGATAGGGGATGGATGTGTGTCCAAGTTTTCTTTGTGCGTCAAGG
GAAATTAATTCAGCGTGATGTTAACCTTTTTCCCTATTATAACGATGCAGAAGAAGATTTCTTAACTTATATGGGGCAAT
TTTACCAAGATAAACAGCATTTCATCCCTAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTGGTAGCCGCTATT
GTGCCAACCAAAATCATCAAACCCAAACGCGGTGAAAAAAAACAACTGGTAGCTTTGGCTACTAAGAATGCTCGTGTTAG
TCTGCAACAAAAATTTGATTTATTAGAAAAAGATATCAAAAAAACGAGTGGTGCTATCGAAAATTTAGGTCAGTTACTTA
GGATTGACAAGCCTGTGCGCATTGAAGCCTTTGATAATTCTAACATTCAAGGGACAAGTCCAGTTGCGGCTATGGTTGTT
TTTGTTGATGGCAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGACCAGATGATTATGCCAG
TATGAGAGAAGTGCTTTTTCGAAGGTACAGTCGGGTGAAAAAGGAGGGACTGCAAGCTCCTAACTTGATTATTGTTGATG
GAGGCGTTGGACAAGTCAATGTGGCCAAAGATGTGATAGAAAAACAACTTGGACTCACTATTCCTGTTGCGGGACTTCAA
AAAAACGATAAGCACCAGACCCATGATTTGCTTTTTGGAAACCCACTTGAAGTTGTACCGTTGCCGCGCCGTTCTGAAGA
GTTTTTCTTACTGCATCGGATTCAAGACGAAGTGCATCGCTTTGCAGTTACATTTCATAGACAAGTGCGACGTAAAAATT
CTTTTTCATCAACATTAGATCATATTTCAGGGCTTGGCCCAAAGCGAAAACAGTTATTACTAAGACACTTTAAAACCATA
ACAGCGATTGCATCAGCTACCTCTGAGGAGATTCAAGCTTTAGGTATACCTAAAACAGTAGTTGAAGCAATACAGCAACA
GATAACAGACAATAAAAATGATAGATCGTCTCCTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

74.024

98.495

0.729
  uvrC Streptococcus pneumoniae R6

74.024

98.495

0.729
  uvrC Streptococcus pneumoniae D39

74.024

98.495

0.729

Multiple sequence alignment