Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   DRA66_RS02635 Genome accession   NZ_CP030825
Coordinates   515200..515868 (+) Length   222 a.a.
NCBI ID   WP_014575282.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 12-208     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 510200..520868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DRA66_RS02615 (DRA66_03010) - 510990..511322 (+) 333 WP_002226445.1 hypothetical protein -
  DRA66_RS02620 (DRA66_03015) - 511654..512163 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  DRA66_RS02625 (DRA66_03030) - 512735..513322 (-) 588 WP_154074380.1 superoxide dismutase -
  DRA66_RS02630 (DRA66_03040) dnaB 513485..514891 (+) 1407 WP_002213843.1 replicative DNA helicase -
  DRA66_RS02635 (DRA66_03045) pilH 515200..515868 (+) 669 WP_014575282.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  DRA66_RS02640 (DRA66_03050) pilV 515898..516518 (+) 621 WP_154074400.1 type IV pilus modification protein PilV Machinery gene
  DRA66_RS02645 (DRA66_03055) pilJ 516515..517513 (+) 999 WP_154074381.1 PilW family protein Machinery gene
  DRA66_RS02650 (DRA66_03060) pilK 517492..518085 (+) 594 WP_002255851.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  DRA66_RS02655 (DRA66_03065) pilX 518090..518563 (+) 474 WP_195183013.1 PilX family type IV pilin Machinery gene
  DRA66_RS02660 (DRA66_03075) - 519443..519871 (-) 429 Protein_510 AzlC family ABC transporter permease -
  DRA66_RS02665 (DRA66_03080) dut 520014..520466 (+) 453 WP_002250021.1 dUTP diphosphatase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24795.30 Da        Isoelectric Point: 9.5822

>NTDB_id=301712 DRA66_RS02635 WP_014575282.1 515200..515868(+) (pilH) [Neisseria meningitidis strain 12-208]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTPN
NKCDSGKKGQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=301712 DRA66_RS02635 WP_014575282.1 515200..515868(+) (pilH) [Neisseria meningitidis strain 12-208]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGCCCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAAATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.068

99.55

0.847

Multiple sequence alignment