Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   ETT64_RS00775 Genome accession   NZ_CP035435
Coordinates   117464..117790 (+) Length   108 a.a.
NCBI ID   WP_011528161.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm64.3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112464..122790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT64_RS00760 (ETT64_00760) - 115096..115461 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT64_RS00765 (ETT64_00765) comGA 115554..116492 (+) 939 WP_063812149.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT64_RS00770 (ETT64_00770) comGB 116428..117462 (+) 1035 WP_227868957.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT64_RS00775 (ETT64_00775) comGC 117464..117790 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT64_RS00780 (ETT64_00780) comGD 117765..118193 (+) 429 WP_136293154.1 competence type IV pilus minor pilin ComGD Machinery gene
  ETT64_RS00785 (ETT64_00785) comGE 118150..118434 (+) 285 WP_315940846.1 competence type IV pilus minor pilin ComGE Machinery gene
  ETT64_RS00790 (ETT64_00790) comGF 118427..118861 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT64_RS00795 (ETT64_00795) comGG 118845..119171 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT64_RS00800 (ETT64_00800) comGH 119269..120222 (+) 954 WP_136293153.1 class I SAM-dependent methyltransferase Machinery gene
  ETT64_RS00805 (ETT64_00805) - 120281..121477 (+) 1197 WP_011284424.1 acetate kinase -
  ETT64_RS00810 (ETT64_00810) - 121664..121972 (+) 309 Protein_111 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12362.29 Da        Isoelectric Point: 9.6949

>NTDB_id=301618 ETT64_RS00775 WP_011528161.1 117464..117790(+) (comGC) [Streptococcus pyogenes strain emm64.3]
MINQWNNLRHKNLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=301618 ETT64_RS00775 WP_011528161.1 117464..117790(+) (comGC) [Streptococcus pyogenes strain emm64.3]
ATGATTAATCAATGGAACAACTTACGACACAAGAATTTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comGC Streptococcus mutans UA159

52.475

93.519

0.491
  comGC Streptococcus mutans UA140

52.475

93.519

0.491
  comGC Streptococcus suis isolate S10

58.025

75

0.435

Multiple sequence alignment