Detailed information NTG0030153

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SPT_RS07805
• Genome accession: NC_012469
• Coordinates: 1493555..1494232 (-)
• Length: 225 a.a.
• NCBI ID: WP_000548959.1
• Uniprot ID: Q9S1K2
• Organism: Streptococcus pneumoniae Taiwan19F-14
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1488555..1499232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPT_RS07775 (SPT_1566)	-	1488717..1489346 (-)	630	WP_000762091.1	NAD(P)-dependent oxidoreductase	-
SPT_RS07780	-	1489584..1489784 (+)	201	WP_001814296.1	hypothetical protein	-
SPT_RS13405	-	1490031..1490212 (+)	182	Protein_1495	hypothetical protein	-
SPT_RS07785 (SPT_1568)	-	1490215..1490355 (+)	141	WP_000422775.1	MazG-like protein	-
SPT_RS07790 (SPT_1569)	-	1490362..1490538 (+)	177	WP_000166031.1	MazG-like protein	-
SPT_RS07795 (SPT_1570)	thrS	1490596..1492539 (+)	1944	WP_000608349.1	threonine--tRNA ligase	-
SPT_RS07800 (SPT_1571)	-	1492588..1493562 (-)	975	WP_000887953.1	HAMP domain-containing histidine kinase	-
SPT_RS07805 (SPT_1572)	braR	1493555..1494232 (-)	678	WP_000548959.1	response regulator transcription factor	Regulator
SPT_RS07810 (SPT_1573)	-	1494388..1495461 (+)	1074	WP_001273832.1	DUF2974 domain-containing protein	-
SPT_RS07815 (SPT_1574)	-	1495552..1495854 (-)	303	WP_000281609.1	hypothetical protein	-
SPT_RS07820 (SPT_1575)	-	1495922..1496359 (-)	438	WP_001166785.1	Rrf2 family transcriptional regulator	-
SPT_RS07825 (SPT_1576)	-	1496435..1497277 (-)	843	WP_000160938.1	metallophosphoesterase	-
SPT_RS07830 (SPT_1577)	-	1497389..1498039 (+)	651	WP_000188505.1	metal-dependent transcriptional regulator	-
SPT_RS13410 (SPT_1578)	-	1498020..1498211 (+)	192	WP_001816503.1	hypothetical protein	-
SPT_RS07840 (SPT_1579)	-	1498237..1498912 (+)	676	Protein_1507	nicotinamide mononucleotide transporter	-
SPT_RS13470	-	1499014..1499085 (+)	72	Protein_1508	glutamine ABC transporter permease	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25964.16 Da
• Isoelectric Point: 5.1362

>NTDB_id=30153 SPT_RS07805 WP_000548959.1 1493555..1494232(-) (braR) [Streptococcus pneumoniae Taiwan19F-14]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide

• Length: 678 bp

>NTDB_id=30153 SPT_RS07805 WP_000548959.1 1493555..1494232(-) (braR) [Streptococcus pneumoniae Taiwan19F-14]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-221)

3D structure

• AlphaFold DB: Q9S1K2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	48.624	96.889	0.471
vicR	Streptococcus mutans UA159	35.319	100	0.369