Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SPT_RS02180 Genome accession   NC_012469
Coordinates   400476..401108 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Taiwan19F-14     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 395476..406108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPT_RS02155 (SPT_0427) mvaD 395753..396706 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  SPT_RS02160 (SPT_0428) - 396693..397700 (+) 1008 WP_000562377.1 phosphomevalonate kinase -
  SPT_RS02165 (SPT_0429) fni 397684..398694 (+) 1011 WP_000210628.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  SPT_RS02170 (SPT_0430) liaF 398772..399470 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  SPT_RS02175 (SPT_0431) - 399467..400462 (+) 996 WP_000743662.1 sensor histidine kinase -
  SPT_RS02180 (SPT_0432) vraR 400476..401108 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  SPT_RS13225 - 401109..401351 (+) 243 Protein_428 DNA alkylation repair protein -
  SPT_RS12915 - 401276..401878 (+) 603 Protein_429 DNA alkylation repair protein -
  SPT_RS02200 (SPT_0436) - 402337..402939 (+) 603 Protein_430 trypsin-like serine peptidase -
  SPT_RS02205 (SPT_0437) - 403241..403600 (+) 360 WP_000378123.1 tyrosine-type recombinase/integrase -
  SPT_RS02210 (SPT_0438) tig 403794..405077 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=30107 SPT_RS02180 WP_000698433.1 400476..401108(+) (vraR) [Streptococcus pneumoniae Taiwan19F-14]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=30107 SPT_RS02180 WP_000698433.1 400476..401108(+) (vraR) [Streptococcus pneumoniae Taiwan19F-14]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41